Ambulatory blood pressure monitoring in 9357 subjects from 11 populations highlights missed opportunities for cardiovascular prevention in women

José Boggia, Lutgarde Thijs, Tine W Hansen, Yan Li, Masahiro Kikuya, Kristina Björklund-Bodegård, Tom Richart, Takayoshi Ohkubo, Jørgen Lykke Jeppesen, Christian Torp-Pedersen, Eamon Dolan, Tatiana Kuznetsova, Agnieszka Olszanecka, Valérie Tikhonoff, Sofia Malyutina, Edoardo Casiglia, Yuri Nikitin, Lars Solskov Lind, Gladys Maestre, Edgardo SandoyaKalina Kawecka-Jaszcz, Yutaka Imai, Jiguang Wang, Hans Ibsen, Eoin O'Brien, Jan A Staessen, International Database on Ambulatory blood pressure in relation to Cardiovascular Outcomes Investigators

109 Citationer (Scopus)

Abstract

To analyze sex-specific relative and absolute risks associated with blood pressure (BP), we performed conventional and 24-hour ambulatory BP measurements in 9357 subjects (mean age, 52.8 years; 47% women) recruited from 11 populations. We computed standardized multivariable-adjusted hazard ratios for associations between outcome and systolic BP. During a course of 11.2 years (median), 1245 participants died, 472 of cardiovascular causes. The number of fatal combined with nonfatal events was 1080, 525, and 458 for cardiovascular and cardiac events and for stroke, respectively. In women and men alike, systolic BP predicted outcome, irrespective of the type of BP measurement. Women compared with men were at lower risk (hazard ratios for death and all cardiovascular events=0.66 and 0.62, respectively; P
OriginalsprogEngelsk
TidsskriftHypertension
Vol/bind57
Udgave nummer3
Sider (fra-til)397-405
Antal sider9
ISSN0194-911X
DOI
StatusUdgivet - 1 mar. 2011

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