Alveolar inflammation in cystic fibrosis

Martina Ulrich; Dieter Worlitzsch; Simona Viglio; Nanna Siegmann; Paolo Iadarola; Janis K Shute; Marianne Geiser; Gerald B Pier; Godehard Friedel; Mark L Barr; Antje Schuster; Keith C Meyer; Felix Ratjen; Thomas Bjarnsholt; Erich Gulbins; Gerd Döring

doi:10.1016/j.jcf.2010.03.001

Alveolar inflammation in cystic fibrosis

Martina Ulrich, Dieter Worlitzsch, Simona Viglio, Nanna Siegmann, Paolo Iadarola, Janis K Shute, Marianne Geiser, Gerald B Pier, Godehard Friedel, Mark L Barr, Antje Schuster, Keith C Meyer, Felix Ratjen, Thomas Bjarnsholt, Erich Gulbins, Gerd Döring

Afdeling for Klinisk Mikrobiologi

103 Citationer (Scopus)

Abstract

In infected lungs of the cystic fibrosis (CF) patients, opportunistic pathogens and mutated cystic fibrosis transmembrane conductance regulator protein (CFTR) contribute to chronic airway inflammation that is characterized by neutrophil/macrophage infiltration, cytokine release and ceramide accumulation. We sought to investigate CF lung inflammation in the alveoli.

Originalsprog	Engelsk
Tidsskrift	Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
Vol/bind	9
Udgave nummer	3
Sider (fra-til)	217-27
Antal sider	11
DOI	https://doi.org/10.1016/j.jcf.2010.03.001
Status	Udgivet - 1 maj 2010

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10.1016/j.jcf.2010.03.001

Citationsformater

Ulrich, M., Worlitzsch, D., Viglio, S., Siegmann, N., Iadarola, P., Shute, J. K., Geiser, M., Pier, G. B., Friedel, G., Barr, M. L., Schuster, A., Meyer, K. C., Ratjen, F., Bjarnsholt, T., Gulbins, E., & Döring, G. (2010). Alveolar inflammation in cystic fibrosis. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 9(3), 217-27. https://doi.org/10.1016/j.jcf.2010.03.001

Ulrich, M, Worlitzsch, D, Viglio, S, Siegmann, N, Iadarola, P, Shute, JK, Geiser, M, Pier, GB, Friedel, G, Barr, ML, Schuster, A, Meyer, KC, Ratjen, F, Bjarnsholt, T, Gulbins, E & Döring, G 2010, 'Alveolar inflammation in cystic fibrosis', Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, bind 9, nr. 3, s. 217-27. https://doi.org/10.1016/j.jcf.2010.03.001

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title = "Alveolar inflammation in cystic fibrosis",

abstract = "In infected lungs of the cystic fibrosis (CF) patients, opportunistic pathogens and mutated cystic fibrosis transmembrane conductance regulator protein (CFTR) contribute to chronic airway inflammation that is characterized by neutrophil/macrophage infiltration, cytokine release and ceramide accumulation. We sought to investigate CF lung inflammation in the alveoli.",

author = "Martina Ulrich and Dieter Worlitzsch and Simona Viglio and Nanna Siegmann and Paolo Iadarola and Shute, {Janis K} and Marianne Geiser and Pier, {Gerald B} and Godehard Friedel and Barr, {Mark L} and Antje Schuster and Meyer, {Keith C} and Felix Ratjen and Thomas Bjarnsholt and Erich Gulbins and Gerd D{\"o}ring",

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T1 - Alveolar inflammation in cystic fibrosis

AU - Ulrich, Martina

AU - Worlitzsch, Dieter

AU - Viglio, Simona

AU - Siegmann, Nanna

AU - Iadarola, Paolo

AU - Shute, Janis K

AU - Geiser, Marianne

AU - Pier, Gerald B

AU - Friedel, Godehard

AU - Barr, Mark L

AU - Schuster, Antje

AU - Meyer, Keith C

AU - Ratjen, Felix

AU - Bjarnsholt, Thomas

AU - Gulbins, Erich

AU - Döring, Gerd

PY - 2010/5/1

Y1 - 2010/5/1

N2 - In infected lungs of the cystic fibrosis (CF) patients, opportunistic pathogens and mutated cystic fibrosis transmembrane conductance regulator protein (CFTR) contribute to chronic airway inflammation that is characterized by neutrophil/macrophage infiltration, cytokine release and ceramide accumulation. We sought to investigate CF lung inflammation in the alveoli.

AB - In infected lungs of the cystic fibrosis (CF) patients, opportunistic pathogens and mutated cystic fibrosis transmembrane conductance regulator protein (CFTR) contribute to chronic airway inflammation that is characterized by neutrophil/macrophage infiltration, cytokine release and ceramide accumulation. We sought to investigate CF lung inflammation in the alveoli.

U2 - 10.1016/j.jcf.2010.03.001

DO - 10.1016/j.jcf.2010.03.001

M3 - Journal article

C2 - 20347403

SN - 1873-5010

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SP - 217

EP - 227

JO - Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

JF - Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society

IS - 3

ER -

Alveolar inflammation in cystic fibrosis

Abstract

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