TY - JOUR
T1 - Alcohol consumption and the risk of self-reported perennial and seasonal allergic rhinitis in young adult women in a population-based cohort study
AU - Bendtsen, P
AU - Grønbaek, M
AU - Kjaer, S K
AU - Munk, C
AU - Linneberg, A
AU - Tolstrup, J S
PY - 2008/7
Y1 - 2008/7
N2 - BACKGROUND: Alcohol consumption has been suggested to be associated with the development of allergic rhinitis (AR), but there is limited data on the topic.OBJECTIVES: The objective of this study was to investigate the association between alcohol consumption and the risk of developing AR among young women.METHODS: Five thousand eight hundred and seventy Danish women aged 20-29 years participated in a prospective cohort study, and were free of seasonal and perennial AR at baseline (1991-1993). Alcohol consumption was assessed by a food frequency questionnaire. The main outcome measures were self-reported information on seasonal and perennial AR debuting during a mean follow-up period of 7.8 years.RESULTS: During follow-up, 831 women developed seasonal AR and 523 women developed perennial AR, corresponding to 14% and 9%. Alcohol consumption was positively associated with the risk of developing perennial AR. The adjusted odds ratio (OR) for perennial AR was 1.78 (95% CI, 1.13-2.80) among women drinking more than 14 drinks/week compared with women drinking <1 drink/week. There was no association between alcohol consumption and seasonal AR. Having one or two parents with asthma was, after adjustment, significantly associated with the risk of developing seasonal (OR, 2.01; 95% CI, 1.65-2.45) and perennial AR (OR, 2.28; 95% CI, 1.70-2.74). Smoking was not associated with an increased risk of developing AR.CONCLUSION: In this population of young adult women, alcohol consumption was associated with an increased risk of developing perennial AR.
AB - BACKGROUND: Alcohol consumption has been suggested to be associated with the development of allergic rhinitis (AR), but there is limited data on the topic.OBJECTIVES: The objective of this study was to investigate the association between alcohol consumption and the risk of developing AR among young women.METHODS: Five thousand eight hundred and seventy Danish women aged 20-29 years participated in a prospective cohort study, and were free of seasonal and perennial AR at baseline (1991-1993). Alcohol consumption was assessed by a food frequency questionnaire. The main outcome measures were self-reported information on seasonal and perennial AR debuting during a mean follow-up period of 7.8 years.RESULTS: During follow-up, 831 women developed seasonal AR and 523 women developed perennial AR, corresponding to 14% and 9%. Alcohol consumption was positively associated with the risk of developing perennial AR. The adjusted odds ratio (OR) for perennial AR was 1.78 (95% CI, 1.13-2.80) among women drinking more than 14 drinks/week compared with women drinking <1 drink/week. There was no association between alcohol consumption and seasonal AR. Having one or two parents with asthma was, after adjustment, significantly associated with the risk of developing seasonal (OR, 2.01; 95% CI, 1.65-2.45) and perennial AR (OR, 2.28; 95% CI, 1.70-2.74). Smoking was not associated with an increased risk of developing AR.CONCLUSION: In this population of young adult women, alcohol consumption was associated with an increased risk of developing perennial AR.
KW - Adult
KW - Alcohol Drinking/adverse effects
KW - Cohort Studies
KW - Denmark/epidemiology
KW - Female
KW - Humans
KW - Logistic Models
KW - Rhinitis, Allergic, Perennial/epidemiology
KW - Rhinitis, Allergic, Seasonal/epidemiology
KW - Risk Factors
KW - Surveys and Questionnaires
U2 - 10.1111/j.1365-2222.2008.02945.x
DO - 10.1111/j.1365-2222.2008.02945.x
M3 - Journal article
C2 - 18294256
SN - 0954-7894
VL - 38
SP - 1179
EP - 1185
JO - Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
JF - Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
IS - 7
ER -