@article{e4673363348944b690062bac0f9d133a,
title = "Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials",
abstract = "The long-term cardioprotective effect of angiotensin receptor blockers (ARBs) is associated with the short-term lowering of its primary target blood pressure, but also with the lowering of albuminuria. Since the individual blood pressure and albuminuria response to an ARB varies between and within an individual, we tested whether the variability and discordance in systolic blood pressure (SBP) and albuminuria response to ARB therapy are associated with its long-term effect on cardiovascular outcomes.",
keywords = "Aged, Albuminuria, Amlodipine, Angiotensin Receptor Antagonists, Biphenyl Compounds, Blood Pressure, Calcium Channel Blockers, Cardiotonic Agents, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Diabetic Nephropathies, Female, Heart Failure, Humans, Hypertension, Losartan, Male, Middle Aged, Myocardial Infarction, Randomized Controlled Trials as Topic, Retrospective Studies, Risk Factors, Stroke, Tetrazoles, Treatment Outcome",
author = "Holtkamp, {Frank A} and {de Zeeuw}, Dick and {de Graeff}, {Pieter A} and Laverman, {Gozewijn D} and Tom Berl and Giuseppe Remuzzi and David Packham and Lewis, {Julia B} and Hans-Henrik Parving and {Lambers Heerspink}, {Hiddo J}",
year = "2011",
doi = "10.1093/eurheartj/ehr017",
language = "English",
volume = "32",
pages = "1493--9",
journal = "European Heart Journal (English Edition)",
issn = "0195-668X",
publisher = "Oxford University Press",
number = "12",
}