Abstract

A newborn female was hospitalized due to metabolic acidosis and conjugated hyperbilirubinaemia. Extrahepatic biliary atresia (EHBA) was suspected why a (99m)Tc-mebrofenin cholescintigraphy was performed. It showed poor hepatocyte tracer uptake and no drainage to the gut. The hepatocyte dysfunction was caused by an obstructing adrenal gland neuroblastoma later visualised by ultrasound and MRI. The cholescintigraphy is a non-invasive modality to exclude or confirm the suspicion of EHBA. Furthermore neonatal conjugated hyperbilirubinaemia demands the use of a multimodality imaging strategy for differential diagnosis to EHBA.
Bidragets oversatte titelAcute, severe liver insufficiency caused by extrahepatic biliary atresia in a newborn
OriginalsprogDansk
TidsskriftUgeskrift for Laeger
Vol/bind175
Udgave nummer17
Sider (fra-til)1195-6
Antal sider2
ISSN0041-5782
StatusUdgivet - 22 apr. 2013

Emneord

  • Acute Disease
  • Adrenal Gland Neoplasms
  • Biliary Atresia
  • Female
  • Hepatic Insufficiency
  • Humans
  • Hyperbilirubinemia, Neonatal
  • Infant, Newborn
  • Neuroblastoma
  • Radiopharmaceuticals
  • Technetium Tc 99m Diethyl-iminodiacetic Acid
  • Treatment Outcome

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