Akral iskæmi med multiple mikrotromber og truende gangræn ved COVID-19-infektion

Mathilde Borring Andersen; Marie Louise Lund; Søren Jacobsen; Thomas Kümler; Stine Simonsen; Pernille Ravn

Akral iskæmi med multiple mikrotromber og truende gangræn ved COVID-19-infektion

Mathilde Borring Andersen, Marie Louise Lund, Søren Jacobsen, Thomas Kümler, Stine Simonsen, Pernille Ravn

3 Citationer (Scopus)

Abstract

This is a report of an atypical presentation of COVID-19. The patient had sparse pulmonary symptoms despite characteristic COVID-19 lesions on CT-thorax and developed severe acral ischaemic change, after a few days of hospitalisation. The condition could not be explained by classical sepsis with hypotension and hypoperfusion, disseminated intravascular coagulation, vasculitis, endocarditis or severe peripheral arteriosclerosis. A skin biopsy showed microthrombosis, interpreted as an activation of the coagulation system associated with COVID-19. Apparently, there are multiple COVID-19 phenotypes.

Bidragets oversatte titel	Acral ischaemia with multiple microthromboses and imminent gangrene in a 73-year-old woman with COVID-19
Originalsprog	Dansk
Artikelnummer	V05200379
Tidsskrift	Ugeskrift for Laeger
Vol/bind	182
Udgave nummer	26
ISSN	0041-5782
Status	Udgivet - 22 jun. 2020

Emneord

Aged
Betacoronavirus
COVID-19
Coronavirus Infections/pathology
Female
Gangrene/virology
Humans
Ischemia/virology
Pandemics
Pneumonia, Viral/pathology
SARS-CoV-2
Thrombosis/virology

Adgang til dokumentet

https://ugeskriftet.dk/videnskab/akral-iskaemi-med-multiple-mikrotromber-og-truende-gangraen-ved-covid-19-infektion

Citationsformater

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title = "Akral isk{\ae}mi med multiple mikrotromber og truende gangr{\ae}n ved COVID-19-infektion",

abstract = "This is a report of an atypical presentation of COVID-19. The patient had sparse pulmonary symptoms despite characteristic COVID-19 lesions on CT-thorax and developed severe acral ischaemic change, after a few days of hospitalisation. The condition could not be explained by classical sepsis with hypotension and hypoperfusion, disseminated intravascular coagulation, vasculitis, endocarditis or severe peripheral arteriosclerosis. A skin biopsy showed microthrombosis, interpreted as an activation of the coagulation system associated with COVID-19. Apparently, there are multiple COVID-19 phenotypes.",

keywords = "Aged, Betacoronavirus, COVID-19, Coronavirus Infections/pathology, Female, Gangrene/virology, Humans, Ischemia/virology, Pandemics, Pneumonia, Viral/pathology, SARS-CoV-2, Thrombosis/virology",

author = "Andersen, {Mathilde Borring} and Lund, {Marie Louise} and S{\o}ren Jacobsen and Thomas K{\"u}mler and Stine Simonsen and Pernille Ravn",

year = "2020",

month = jun,

day = "22",

language = "Dansk",

volume = "182",

journal = "Ugeskrift for Laeger",

issn = "0041-5782",

publisher = "Almindelige Danske Laegeforening",

number = "26",

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TY - JOUR

T1 - Akral iskæmi med multiple mikrotromber og truende gangræn ved COVID-19-infektion

AU - Andersen, Mathilde Borring

AU - Lund, Marie Louise

AU - Jacobsen, Søren

AU - Kümler, Thomas

AU - Simonsen, Stine

AU - Ravn, Pernille

PY - 2020/6/22

Y1 - 2020/6/22

N2 - This is a report of an atypical presentation of COVID-19. The patient had sparse pulmonary symptoms despite characteristic COVID-19 lesions on CT-thorax and developed severe acral ischaemic change, after a few days of hospitalisation. The condition could not be explained by classical sepsis with hypotension and hypoperfusion, disseminated intravascular coagulation, vasculitis, endocarditis or severe peripheral arteriosclerosis. A skin biopsy showed microthrombosis, interpreted as an activation of the coagulation system associated with COVID-19. Apparently, there are multiple COVID-19 phenotypes.

AB - This is a report of an atypical presentation of COVID-19. The patient had sparse pulmonary symptoms despite characteristic COVID-19 lesions on CT-thorax and developed severe acral ischaemic change, after a few days of hospitalisation. The condition could not be explained by classical sepsis with hypotension and hypoperfusion, disseminated intravascular coagulation, vasculitis, endocarditis or severe peripheral arteriosclerosis. A skin biopsy showed microthrombosis, interpreted as an activation of the coagulation system associated with COVID-19. Apparently, there are multiple COVID-19 phenotypes.

KW - Aged

KW - Betacoronavirus

KW - COVID-19

KW - Coronavirus Infections/pathology

KW - Female

KW - Gangrene/virology

KW - Humans

KW - Ischemia/virology

KW - Pandemics

KW - Pneumonia, Viral/pathology

KW - SARS-CoV-2

KW - Thrombosis/virology

M3 - Tidsskriftartikel

C2 - 32584760

SN - 0041-5782

VL - 182

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 26

M1 - V05200379

ER -

Akral iskæmi med multiple mikrotromber og truende gangræn ved COVID-19-infektion

Abstract

Emneord

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