Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Age, cancer site and gender associations with symptoms and problems in specialised palliative care: a large, nationwide, register-based study

Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

  1. Dansk Palliativ Database

    Projekt: Typer af projekterProjekt

  1. Early specialised palliative care: interventions, symptoms, problems

    Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

  2. Oncology to specialised palliative home care systematic transition: the Domus randomised trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

  3. Clinical research in cancer palliative care: a metaresearch analysis

    Publikation: Bidrag til tidsskriftTidsskriftartikelpeer review

  4. Bereaved caregivers of patients with high-grade glioma: a systematic review

    Publikation: Bidrag til tidsskriftReviewpeer review

Vis graf over relationer

BACKGROUND: Patients referred to specialised palliative care are troubled by symptoms/problems, but more knowledge is needed on the level and frequency of symptoms/problems. It is also uncertain how gender, age and cancer diagnosis, respectively, are associated with symptoms/problems.

AIMS: To describe symptoms/problems in patients with cancer at the start of specialised palliative care, and to study how age, gender and cancer diagnosis were associated with symptoms/problems.

DESIGN: A register-based study including data from the Danish Palliative Care Database.

SETTING/PARTICIPANTS: Patients with cancer who reported their symptoms/problems using the European Organisation for Research and Treatment of Cancer Quality of Life Questionaire-Core-15-Palliative Care (EORTC QLQ-C15-PAL) at the start of specialised palliative care were included. Ordinal logistic regression was performed to test if gender, age and cancer diagnosis were associated with each symptom/problem.

RESULTS: 31 771 patients with cancer were included in the study. The most prevalent and severe symptoms/problems were pain, appetite loss, fatigue, poor physical function and poor quality of life. Gender, age and cancer diagnosis were significantly associated with most symptoms/problems. The strongest associations between symptoms/problems and gender and age, respectively, were increased risk of nausea in women, as well as increased risk of poor physical function and reduced risk of sleeplessness and pain with increasing age. Patients with brain/central nervous system cancer had the lowest risk of symptoms but the highest risk of poor physical function.

CONCLUSION: At the start of specialised palliative care, patients with cancer experience severe levels of symptoms, poor physical function and poor quality of life. Age, gender and diagnosis were significantly associated with most symptoms/problems, but the strength and direction of the associations differed across symptoms/problems.

OriginalsprogEngelsk
TidsskriftBMJ Supportive and Palliative Care
Vol/bind12
Sider (fra-til)e201-e210
Antal sider10
ISSN2045-435X
DOI
StatusUdgivet - 1 jul. 2022

Bibliografisk note

© Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.

ID: 61360963