@article{83542936a196426c833efa65c7d13543,
title = "Adverse effects of biologics: a network meta-analysis and Cochrane overview",
abstract = "Biologics are used for the treatment of rheumatoid arthritis and many other conditions. While the efficacy of biologics has been established, there is uncertainty regarding the adverse effects of this treatment. Since serious risks such as tuberculosis (TB) reactivation, serious infections, and lymphomas may be common to the biologics but occur in small numbers across the various indications, we planned to combine the results from biologics used in many conditions to obtain the much needed risk estimates.",
keywords = "Antibodies, Monoclonal, Biological Products, Humans, Immunologic Factors, Patient Dropouts, Randomized Controlled Trials as Topic",
author = "Singh, {Jasvinder A} and Wells, {George A} and Robin Christensen and {Tanjong Ghogomu}, Elizabeth and Lara Maxwell and Macdonald, {John K} and Graziella Filippini and Nicole Skoetz and Damian Francis and Lopes, {Luciane C} and Guyatt, {Gordon H} and Jochen Schmitt and {La Mantia}, Loredana and Tobias Weberschock and Roos, {Juliana F} and Hendrik Siebert and Sarah Hershan and Lunn, {Michael Pt} and Peter Tugwell and Rachelle Buchbinder",
year = "2011",
month = jan,
day = "1",
doi = "10.1002/14651858.CD008794.pub2",
language = "English",
pages = "CD008794",
journal = "Cochrane Database of Systematic Reviews",
issn = "1469-493X",
publisher = "Update Software Ltd",
number = "2",
}