adiposetissue.org: A knowledge portal integrating clinical and experimental data from human adipose tissue

Jiawei Zhong; Danae Zareifi; Sophie Weinbrenner; Mattias Hansen; Felix Klingelhuber; Pamela A Nono Nankam; Scott Frendo-Cumbo; Nayanika Bhalla; Lina Cordeddu; Thais de Castro Barbosa; Peter Arner; Ingrid Dahlman; Maheswary Muniandy; Sini Heinonen; Kirsi H Pietiläinen; Anne Hoffmann; Adhideb Ghosh; Dorit John; Anke Tönjes; Patrik L Ståhl; Yvonne Böttcher; Maria Keller; Peter Kovacs; Alastair G Kerr; Dominique Langin; Christian Wolfrum; Matthias Blüher; Natalie Krahmer; Lucas Massier; Niklas Mejhert; Mikael Rydén

doi:10.1016/j.cmet.2025.01.012

adiposetissue.org: A knowledge portal integrating clinical and experimental data from human adipose tissue

Jiawei Zhong, Danae Zareifi, Sophie Weinbrenner, Mattias Hansen, Felix Klingelhuber, Pamela A Nono Nankam, Scott Frendo-Cumbo, Nayanika Bhalla, Lina Cordeddu, Thais de Castro Barbosa, Peter Arner, Ingrid Dahlman, Maheswary Muniandy, Sini Heinonen, Kirsi H Pietiläinen, Anne Hoffmann, Adhideb Ghosh, Dorit John, Anke Tönjes, Patrik L StåhlYvonne Böttcher, Maria Keller, Peter Kovacs, Alastair G Kerr, Dominique Langin, Christian Wolfrum, Matthias Blüher, Natalie Krahmer, Lucas Massier^*, Niklas Mejhert^*, Mikael Rydén^*

^*Corresponding author af dette arbejde

Steno Diabetes Center Copenhagen

14 Citationer (Scopus)

Abstract

We developed the Adipose Tissue Knowledge Portal by centralizing previously dispersed datasets, integrating clinical and experimental results with transcriptomic and proteomic data from >6,000 women and men. The platform includes multiple adipose depots, resident cell types, and adipocyte perturbation studies. By providing streamlined data access, the portal enables integrative analyses and serves as a powerful tool to interrogate various dimensions of adipose biology down to the single-cell level.

Originalsprog	Engelsk
Tidsskrift	Cell Metabolism
Vol/bind	37
Udgave nummer	3
Sider (fra-til)	566-569
Antal sider	4
ISSN	1550-4131
DOI	https://doi.org/10.1016/j.cmet.2025.01.012
Status	Udgivet - 4 mar. 2025

Adgang til dokumentet

10.1016/j.cmet.2025.01.012Licens: Ikke-specificeret

Andre filer og links

Link to publication in Scopus

Citationsformater

Zhong, J., Zareifi, D., Weinbrenner, S., Hansen, M., Klingelhuber, F., Nono Nankam, P. A., Frendo-Cumbo, S., Bhalla, N., Cordeddu, L., de Castro Barbosa, T., Arner, P., Dahlman, I., Muniandy, M., Heinonen, S., Pietiläinen, K. H., Hoffmann, A., Ghosh, A., John, D., Tönjes, A., ... Rydén, M. (2025). adiposetissue.org: A knowledge portal integrating clinical and experimental data from human adipose tissue. Cell Metabolism, 37(3), 566-569. https://doi.org/10.1016/j.cmet.2025.01.012

Zhong, J, Zareifi, D, Weinbrenner, S, Hansen, M, Klingelhuber, F, Nono Nankam, PA, Frendo-Cumbo, S, Bhalla, N, Cordeddu, L, de Castro Barbosa, T, Arner, P, Dahlman, I, Muniandy, M, Heinonen, S, Pietiläinen, KH, Hoffmann, A, Ghosh, A, John, D, Tönjes, A, Ståhl, PL, Böttcher, Y, Keller, M, Kovacs, P, Kerr, AG, Langin, D, Wolfrum, C, Blüher, M, Krahmer, N, Massier, L, Mejhert, N & Rydén, M 2025, 'adiposetissue.org: A knowledge portal integrating clinical and experimental data from human adipose tissue', Cell Metabolism, bind 37, nr. 3, s. 566-569. https://doi.org/10.1016/j.cmet.2025.01.012

@article{d0b77d7690d04650b319c285f21f556b,

title = "adiposetissue.org: A knowledge portal integrating clinical and experimental data from human adipose tissue",

abstract = "We developed the Adipose Tissue Knowledge Portal by centralizing previously dispersed datasets, integrating clinical and experimental results with transcriptomic and proteomic data from >6,000 women and men. The platform includes multiple adipose depots, resident cell types, and adipocyte perturbation studies. By providing streamlined data access, the portal enables integrative analyses and serves as a powerful tool to interrogate various dimensions of adipose biology down to the single-cell level.",

keywords = "Humans, Adipose Tissue/metabolism, Female, Male, Transcriptome, Proteomics, Adipocytes/metabolism",

author = "Jiawei Zhong and Danae Zareifi and Sophie Weinbrenner and Mattias Hansen and Felix Klingelhuber and {Nono Nankam}, {Pamela A} and Scott Frendo-Cumbo and Nayanika Bhalla and Lina Cordeddu and {de Castro Barbosa}, Thais and Peter Arner and Ingrid Dahlman and Maheswary Muniandy and Sini Heinonen and Pietil{\"a}inen, {Kirsi H} and Anne Hoffmann and Adhideb Ghosh and Dorit John and Anke T{\"o}njes and St{\aa}hl, {Patrik L} and Yvonne B{\"o}ttcher and Maria Keller and Peter Kovacs and Kerr, {Alastair G} and Dominique Langin and Christian Wolfrum and Matthias Bl{\"u}her and Natalie Krahmer and Lucas Massier and Niklas Mejhert and Mikael Ryd{\'e}n",

year = "2025",

month = mar,

day = "4",

doi = "10.1016/j.cmet.2025.01.012",

language = "English",

volume = "37",

pages = "566--569",

journal = "Cell Metabolism",

issn = "1550-4131",

publisher = "Cell Press",

number = "3",

}

TY - JOUR

T1 - adiposetissue.org

T2 - A knowledge portal integrating clinical and experimental data from human adipose tissue

AU - Zhong, Jiawei

AU - Zareifi, Danae

AU - Weinbrenner, Sophie

AU - Hansen, Mattias

AU - Klingelhuber, Felix

AU - Nono Nankam, Pamela A

AU - Frendo-Cumbo, Scott

AU - Bhalla, Nayanika

AU - Cordeddu, Lina

AU - de Castro Barbosa, Thais

AU - Arner, Peter

AU - Dahlman, Ingrid

AU - Muniandy, Maheswary

AU - Heinonen, Sini

AU - Pietiläinen, Kirsi H

AU - Hoffmann, Anne

AU - Ghosh, Adhideb

AU - John, Dorit

AU - Tönjes, Anke

AU - Ståhl, Patrik L

AU - Böttcher, Yvonne

AU - Keller, Maria

AU - Kovacs, Peter

AU - Kerr, Alastair G

AU - Langin, Dominique

AU - Wolfrum, Christian

AU - Blüher, Matthias

AU - Krahmer, Natalie

AU - Massier, Lucas

AU - Mejhert, Niklas

AU - Rydén, Mikael

PY - 2025/3/4

Y1 - 2025/3/4

N2 - We developed the Adipose Tissue Knowledge Portal by centralizing previously dispersed datasets, integrating clinical and experimental results with transcriptomic and proteomic data from >6,000 women and men. The platform includes multiple adipose depots, resident cell types, and adipocyte perturbation studies. By providing streamlined data access, the portal enables integrative analyses and serves as a powerful tool to interrogate various dimensions of adipose biology down to the single-cell level.

AB - We developed the Adipose Tissue Knowledge Portal by centralizing previously dispersed datasets, integrating clinical and experimental results with transcriptomic and proteomic data from >6,000 women and men. The platform includes multiple adipose depots, resident cell types, and adipocyte perturbation studies. By providing streamlined data access, the portal enables integrative analyses and serves as a powerful tool to interrogate various dimensions of adipose biology down to the single-cell level.

KW - Humans

KW - Adipose Tissue/metabolism

KW - Female

KW - Male

KW - Transcriptome

KW - Proteomics

KW - Adipocytes/metabolism

UR - http://www.scopus.com/inward/record.url?scp=85218641432&partnerID=8YFLogxK

U2 - 10.1016/j.cmet.2025.01.012

DO - 10.1016/j.cmet.2025.01.012

M3 - Comment/debate

C2 - 39983713

SN - 1550-4131

VL - 37

SP - 566

EP - 569

JO - Cell Metabolism

JF - Cell Metabolism

IS - 3

ER -

adiposetissue.org: A knowledge portal integrating clinical and experimental data from human adipose tissue

Abstract

Adgang til dokumentet

Andre filer og links

Fingeraftryk

Citationsformater