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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Acute reduction of lipolysis reduces adiponectin and IL-18: evidence from an intervention study with acipimox and insulin

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

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Low-grade inflammation is a feature of chronic diseases such as type 2 diabetes and lipodystrophy. It is associated with abdominal adiposity, increased levels of NEFA, hyperinsulinaemia and low adiponectin levels. However, the causal relationship between impaired metabolism and inflammation is not understood. We explored the anti-lipolytic effect of acipimox and insulin on adiponectin and adipocyte-associated cytokines in patients with lipodystrophy.
OriginalsprogEngelsk
TidsskriftDiabetologia
Vol/bind56
Udgave nummer9
Sider (fra-til)2034-43
Antal sider10
ISSN0012-186X
DOI
StatusUdgivet - sep. 2013

ID: 43144609