Acute posterior multifocal placoid pigment epitheliopathy resembling multiple sclerosis

Sahla El Mahdaoui*, Asher Lou Isenberg, Klaus Hansen, Annika Reynberg Langkilde, Steffen Hamann, Jeppe Romme Christensen

*Corresponding author af dette arbejde

Abstract

A 23-year-old man presented with right eye blurred vision; he was diagnosed with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), and his symptoms resolved with prednisolone. Two months later, he developed a right arm weakness that resolved after 3 weeks. MR scan of brain identified changes suggesting multiple sclerosis, with four hyperintense FLAIR lesions; there was contrast enhancement of two lesions and no diffusion restriction. Cerebrospinal fluid showed mononuclear pleocytosis. We eventually diagnosed these as APMPPE-associated CNS lesions. APMPPE is a rare inflammatory chorioretinopathy that rarely can resemble multiple sclerosis clinically and radiologically.

OriginalsprogEngelsk
TidsskriftPractical Neurology
Vol/bind22
Udgave nummer6
Sider (fra-til)515-517
Antal sider3
ISSN1474-7758
DOI
StatusUdgivet - 2022

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