Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Acute Lymphoblastic Leukemia Presenting With Pancytopenia Followed by a 14-Month-Long Period of Transient Remission Possibly Supporting the Adrenal Hypothesis of Leukemogenesis

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Hearing Status in Survivors of Childhood Acute Myeloid Leukemia Treated With Chemotherapy Only: A NOPHO-AML Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Liposomal Cytarabine Induces Less Neurocognitive Dysfunction Than Intrathecal Methotrexate in an Animal Model

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Hepatotoxicity During Maintenance Therapy and Prognosis in Children With Acute Lymphoblastic Leukemia

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Successful Treatment of Rhino-Orbital-Cerebral Mucormycosis in a Child With Leukemia

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Identification of the novel HLA allele, HLA-C*07:780, identified in a Danish woman

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Proinflammatory CD20+ T cells in the pathogenesis of multiple sclerosis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

A small group of children with acute lymphoblastic leukemia (ALL) have a preleukemic phase of pancytopenia followed by a period of spontaneous remission before the diagnosis (pre-ALL). A 6-year-old girl presented with pancytopenia, fever, and myelodysplasia. Following transient remission pre-B ALL was diagnosed 14 months later. Clonal B-lineage blasts at the period of pancytopenia were identified retrospectively. The interval between pre-ALL and ALL-diagnosis was longer than previously reported. The infection was clinically severe and might have induced a significant endogenous corticosteroids production resulting in the long-lasting remission. The case supports the adrenal and the Coley's toxin hypothesis in leukemogenesis.

OriginalsprogEngelsk
TidsskriftJournal of Pediatric Hematology / Oncology
Vol/bind38
Udgave nummer8
Sider (fra-til)e271-e273
ISSN1077-4114
DOI
StatusUdgivet - nov. 2016

ID: 49162140