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Activated platelets enhance IL-10 secretion and reduce TNF-α secretion by monocytes

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Vis graf over relationer
Activated platelets are known to modulate immune responses by secreting or shedding a range of immunomodulatory substances. We examined the influence of activated platelets on cytokine production by normal human mononuclear cells, induced by tetanus toxoid (TT), human thyroglobulin (TG), Escherichia coli LPS, or intact Porphyromonas gingivalis. Addition of platelets activated by thrombin-receptor-activating peptide enhanced IL-10 production induced by LPS (p
OriginalsprogEngelsk
TidsskriftJournal of immunology (Baltimore, Md. : 1950)
Vol/bind191
Udgave nummer8
Sider (fra-til)4059-67
Antal sider9
ISSN0022-1767
DOI
StatusUdgivet - 15 okt. 2013

ID: 42807074