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Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

Acquired resistance to cancer immunotherapy

Publikation: Bidrag til tidsskriftReviewForskningpeer review

DOI

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In recent times, advances in cancer immunotherapy have yielded impressive, durable clinical responses in patients with varied subtypes of cancer. However, a significant proportion of patients who initially demonstrate encouraging tumor regression develop resistance and progress over time. The identification of novel therapeutic approaches to overcome resistance may result in significantly improved clinical outcomes and remains an area of high scientific priority. This review aims to summarize the current knowledge regarding the role of both tumor-intrinsic and tumor-extrinsic factors in the development of resistance to cancer immunotherapy and to discuss current and possible future therapeutic strategies targeting these mechanisms.

OriginalsprogEngelsk
TidsskriftSeminars in Immunopathology
Vol/bind41
Udgave nummer1
Sider (fra-til)31-40
Antal sider10
ISSN1863-2297
DOI
StatusUdgivet - jan. 2019

ID: 54806831