Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
E-pub ahead of print

Academic performance in adolescents born to mothers with gestational diabetes - a national Danish cohort study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Expression of cholecystokinin and its receptors in the intestinal tract of type 2 diabetes patients and healthy controls

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Elevated apolipoprotein A1 and HDL cholesterol associated with age-related macular degeneration: 2 population cohorts

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Prenatal Exposure to Butyl Paraben Is Associated With Fat Percentage in 7-Year-Old Boys

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Serum insulin-like factor 3 levels are reduced in former androgen users suggesting impaired Leydig cell capacity

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Treatment of Hyperthyroidism Reduces Systemic Oxidative Stress, as Measured by Markers of RNA and DNA Damage

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

CONTEXT: The prevalence of Gestational Diabetes Mellitus (GDM) is increasing, and intrauterine hyperglycemia is suspected to affect offspring cognitive function.

OBJECTIVE: We assessed academic performance by grade point average (GPA) in children aged 15-16 years at compulsory school graduation, comparing offspring exposed to GDM (O-GDM) with offspring from the background population (O-BP).

DESIGN: Cohort study.

SETTING: Register-based.

PARTICIPANTS: All singletons born in Denmark between 1994 and 2001 (O-GDM: n=4,286; O-BP: n=501,045). Standardized and internationally comparable GPAs were compared in univariate- and multivariate linear models.

MAIN OUTCOME MEASURES: Adjusted mean difference in GPA. We additionally analyzed the probability of having a high GPA, a GPA below passing, and no GPA registered.

RESULTS: O-GDM had a GPA of 6.29 (SD 2.52), while O-BP had a GPA of 6.78 (SD 2.50). The adjusted mean difference was -0.36 [95% confidence interval (CI) -0.44; -0.29], corresponding to a Cohens D of 0.14. O-GDM had a lower probability of obtaining a high GPA (adjusted odds ratio (aOR) 0.68 [95 CI 0.59; 0.79]), while their risk of obtaining a GPA below passing was similar to O-BP (aOR 1.20 [95 CI 0.96; 1.50]). O-GDM had a higher risk of not having a GPA registered (aOR of 1.38 [95% CI 1.24; 1.53]).

CONCLUSION: Academic performance in O-GDM was marginally lower than in O-BP. However, this difference is unlikely to be of clinical importance.

OriginalsprogEngelsk
TidsskriftThe Journal of clinical endocrinology and metabolism
ISSN0021-972X
DOI
StatusE-pub ahead of print - 22 jun. 2021

ID: 66575773