A simple method to quantitate IP-10 in dried blood and plasma spots

Martine G Aabye; Jesper Eugen-Olsen; Anne Marie Werlinrud; Line Lindebo Holm; Tamara Tuuminen; Pernille Ravn; Morten Ruhwald

doi:10.1371/journal.pone.0039228

A simple method to quantitate IP-10 in dried blood and plasma spots

Martine G Aabye, Jesper Eugen-Olsen, Anne Marie Werlinrud, Line Lindebo Holm, Tamara Tuuminen, Pernille Ravn, Morten Ruhwald

Klinisk Forskningsafdeling AHH

40 Citationer (Scopus)

Abstract

Antigen specific release of IP-10 is an established marker for infection with M.tuberculosis. Compared to IFN-γ, IP-10 is released in 100-fold higher concentrations enabling the development of novel assays for detection. Dried blood spots are a convenient sample for high throughput newborn screening.

Originalsprog	Engelsk
Tidsskrift	P L o S One
Vol/bind	7
Udgave nummer	6
Sider (fra-til)	e39228
ISSN	1932-6203
DOI	https://doi.org/10.1371/journal.pone.0039228
Status	Udgivet - 2012

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10.1371/journal.pone.0039228

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abstract = "Antigen specific release of IP-10 is an established marker for infection with M.tuberculosis. Compared to IFN-γ, IP-10 is released in 100-fold higher concentrations enabling the development of novel assays for detection. Dried blood spots are a convenient sample for high throughput newborn screening.",

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AU - Aabye, Martine G

AU - Eugen-Olsen, Jesper

AU - Werlinrud, Anne Marie

AU - Holm, Line Lindebo

AU - Tuuminen, Tamara

AU - Ravn, Pernille

AU - Ruhwald, Morten

PY - 2012

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N2 - Antigen specific release of IP-10 is an established marker for infection with M.tuberculosis. Compared to IFN-γ, IP-10 is released in 100-fold higher concentrations enabling the development of novel assays for detection. Dried blood spots are a convenient sample for high throughput newborn screening.

AB - Antigen specific release of IP-10 is an established marker for infection with M.tuberculosis. Compared to IFN-γ, IP-10 is released in 100-fold higher concentrations enabling the development of novel assays for detection. Dried blood spots are a convenient sample for high throughput newborn screening.

U2 - 10.1371/journal.pone.0039228

DO - 10.1371/journal.pone.0039228

M3 - Journal article

C2 - 22761744

SN - 1932-6203

VL - 7

SP - e39228

JO - P L o S One

JF - P L o S One

IS - 6

ER -

A simple method to quantitate IP-10 in dried blood and plasma spots

Abstract

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