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A prospective international Aspergillus terreus survey: an EFISG, ISHAM and ECMM joint study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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  • B Risslegger
  • T Zoran
  • M Lackner
  • M Aigner
  • F Sánchez-Reus
  • A Rezusta
  • A Chowdhary
  • S J Taj-Aldeen
  • M C Arendrup
  • S Oliveri
  • D P Kontoyiannis
  • A Alastruey-Izquierdo
  • K Lagrou
  • G Lo Cascio
  • J F Meis
  • W Buzina
  • C Farina
  • M Drogari-Apiranthitou
  • A Grancini
  • A M Tortorano
  • B Willinger
  • A Hamprecht
  • E Johnson
  • L Klingspor
  • V Arsic-Arsenijevic
  • O A Cornely
  • J Meletiadis
  • W Prammer
  • V Tullio
  • J-J Vehreschild
  • L Trovato
  • R E Lewis
  • E Segal
  • P-M Rath
  • P Hamal
  • M Rodriguez-Iglesias
  • E Roilides
  • S Arikan-Akdagli
  • A Chakrabarti
  • A L Colombo
  • M S Fernández
  • M T Martin-Gomez
  • H Badali
  • G Petrikkos
  • N Klimko
  • S M Heimann
  • J Houbraken
  • O Uzun
  • M Edlinger
  • S de la Fuente
  • C Lass-Flörl
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OBJECTIVES: A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections.

METHODS: A total of 370 cases from 21 countries were evaluated.

RESULTS: The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L).

CONCLUSIONS: Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.

OriginalsprogEngelsk
TidsskriftClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Vol/bind23
Udgave nummer10
Sider (fra-til)776.e1-776.e5
ISSN1198-743X
DOI
StatusUdgivet - okt. 2017

ID: 52705100