Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

A prospective 52-week randomized controlled trial of patient-initiated care consultations for patients with psoriasis

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Sleep disturbance in psoriasis: a case-controlled study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Short contact with nickel causes allergic contact dermatitis: an experimental study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Association Between Topical Corticosteroid Use and Type 2 Diabetes in Two European Population-Based Adult Cohorts

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Temporal changes in chromium allergy in Denmark between 2002 and 2017

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. The effect of anti-IL-17 treatment on the reaction to a nickel patch test in patients with allergic contact dermatitis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Increase in Vitamin D but not Regulatory T Cells following Ultraviolet B Phototherapy of Patients with Atopic Dermatitis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Fast-track pneumonia pathway focusing on early progressive mobilisation: a clinical feasibility study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

BACKGROUND: Treatment and care of moderate-to-severe psoriasis require lifelong consultations with a dermatologist with close monitoring of systemic treatment.

OBJECTIVES: To investigate the effect of patient-initiated care consultation (PICC) for patients with psoriasis in a dermatology outpatient clinic.

METHODS: A prospective randomized controlled trial with patients on well-controlled systemic treatment randomized to either (i) the PICC group, where they participated in one annual consultation with a dermatologist but were able to initiate consultations when needed; or (ii) routine care, where they participated in a consultation every 12-16 weeks. The primary outcome was the Dermatology Life Quality Index (DLQI). Other outcomes were safety, patient adherence and satisfaction with healthcare assessed at baseline and after 52 weeks. The study was registered with clinical trials number NCT02382081.

RESULTS: In total 150 patients were included, with 58·0% treated with biologics, 37·3% with methotrexate and 4·7% with acitretin. At week 52 no statistically significant mean difference between groups was detected in DLQI (0·28, 95% confidence interval -0·35 to 0·9) or Psoriasis Area and Severity Index (-0·24, 95% confidence interval -0·84 to 0·36). Patients in the PICC group requested 63% fewer consultations with a dermatologist: mean 2·5 ± 0·1 vs. 5·1 ± 0·6 (P = 0·001). Patient adherence and safety with treatment monitoring were equal between groups, but the PICC group was significantly better at attending consultations than the control group (P = 0·003).

CONCLUSIONS: PICC offers additional clinical benefits over routine care, making patients less dependent on clinical visits. The intervention adds no harm to monitoring systemic treatment, and patients report high quality of life and satisfaction with healthcare.

OriginalsprogEngelsk
TidsskriftBritish Journal of Dermatology
Vol/bind179
Udgave nummer2
Sider (fra-til)301-308
Antal sider8
ISSN0007-0963
DOI
StatusUdgivet - aug. 2018

ID: 55280002