Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

A meta-analysis of HLA-antigen prevalences in alcoholics and alcoholic liver disease

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Adult-Life Alcohol Consumption and Age-Related Cognitive Decline from Early Adulthood to Late Midlife

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Acute Pancreatitis: Impact of Alcohol Consumption and Seasonal Factors

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Epidemiology of alcoholic liver disease in Denmark 2006-2011: a population-based study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Plasma YKL-40 in Inuit and Danes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  5. Physical Activity and Risk of Alcohol Use Disorders: Results from a Prospective Cohort Study

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Letter to the Editor: Glucocorticosteroids for Alcohol-Associated Hepatitis

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Prognosis and Reclassification by YKL-40 in Stable Coronary Artery Disease

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer
In the search for genetic factors influencing susceptibility to the development of alcoholism and alcoholic liver disease, 28 studies have been published analysing the distribution of human leucocyte antigens (HLA) in alcoholics compared to healthy controls. A number of HLA-phenotypes has been suspected of being associated with both alcoholism and alcoholic liver disease. In the present study a meta-analysis is carried out on the data from these studies, subdivided according to race and degree of liver injury. The conclusion is that none of the HLA-phenotypes so far investigated in Caucasians can be shown to be significantly more common in any of the studied patient categories than in controls, whereas the results of Japanese studies are less clear. The limitations of the data material and the design of the studies are discussed, as well as the strength and limitations of the method of meta-analysis.
OriginalsprogEngelsk
TidsskriftAlcohol and Alcoholism
Vol/bind29
Udgave nummer6
Sider (fra-til)757-64
Antal sider8
ISSN0735-0414
StatusUdgivet - nov. 1994

ID: 38931475