Forskning
Udskriv Udskriv
Switch language
Region Hovedstaden - en del af Københavns Universitetshospital
Udgivet

A low-gluten diet induces changes in the intestinal microbiome of healthy Danish adults

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

DOI

  1. Combined burden and functional impact tests for cancer driver discovery using DriverPower

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. Genomic footprints of activated telomere maintenance mechanisms in cancer

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Pathway and network analysis of more than 2500 whole cancer genomes

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  4. Prenatal dietary supplements influence the infant airway microbiota in a randomized factorial clinical trial

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  1. Gain-of-function mutation in the voltage-gated potassium channel gene KCNQ1 and glucose-stimulated hypoinsulinemia - case report

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  2. GIP and GLP-1 Receptor Antagonism During a Meal in Healthy Individuals

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Sex-specific estrogen levels and reference intervals from infancy to late adulthood determined by LC-MS/MS

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

Vis graf over relationer

Adherence to a low-gluten diet has become increasingly common in parts of the general population. However, the effects of reducing gluten-rich food items including wheat, barley and rye cereals in healthy adults are unclear. Here, we undertook a randomised, controlled, cross-over trial involving 60 middle-aged Danish adults without known disorders with two 8-week interventions comparing a low-gluten diet (2 g gluten per day) and a high-gluten diet (18 g gluten per day), separated by a washout period of at least six weeks with habitual diet (12 g gluten per day). We find that, in comparison with a high-gluten diet, a low-gluten diet induces moderate changes in the intestinal microbiome, reduces fasting and postprandial hydrogen exhalation, and leads to improvements in self-reported bloating. These observations suggest that most of the effects of a low-gluten diet in non-coeliac adults may be driven by qualitative changes in dietary fibres.

OriginalsprogEngelsk
TidsskriftNature Communications
Vol/bind9
Udgave nummer4630
Sider (fra-til)4630
ISSN2041-1723
DOI
StatusUdgivet - 13 nov. 2018

ID: 55630181