TY - JOUR
T1 - A hybrid register and questionnaire study of Covid-19 and post-acute sick leave in Denmark
AU - O'Regan, Elisabeth
AU - Svalgaard, Ingrid Bech
AU - Sørensen, Anna Irene Vedel
AU - Spiliopoulos, Lampros
AU - Bager, Peter
AU - Nielsen, Nete Munk
AU - Hansen, Jørgen Vinsløv
AU - Koch, Anders
AU - Ethelberg, Steen
AU - Hviid, Anders
N1 - © 2023. Springer Nature Limited.
PY - 2023/10/7
Y1 - 2023/10/7
N2 - Post-acute sick leave is an underexplored indicator of the societal burden of SARS-CoV-2. Here, we report findings about self-reported sick leave and risk factors thereof from a hybrid survey and register study, which include 37,482 RT-PCR confirmed SARS-CoV-2 cases and 51,336 test-negative controls who were tested during the index- and alpha-dominant waves. We observe that an additional 33 individuals per 1000 took substantial sick leave following acute infection compared to persons with no known history of infection, where substantial sick leave is defined as >1 month of sick leave within the period 1-9 months after the RT-PCR test date. Being female, 50-65 years, or having certain pre-existing health conditions such as obesity, chronic lung diseases, and fibromyalgia each increase risk for taking substantial sick leave. Altogether, these results may help motivate improved diagnostic and treatment options for persons living with post-Covid conditions.
AB - Post-acute sick leave is an underexplored indicator of the societal burden of SARS-CoV-2. Here, we report findings about self-reported sick leave and risk factors thereof from a hybrid survey and register study, which include 37,482 RT-PCR confirmed SARS-CoV-2 cases and 51,336 test-negative controls who were tested during the index- and alpha-dominant waves. We observe that an additional 33 individuals per 1000 took substantial sick leave following acute infection compared to persons with no known history of infection, where substantial sick leave is defined as >1 month of sick leave within the period 1-9 months after the RT-PCR test date. Being female, 50-65 years, or having certain pre-existing health conditions such as obesity, chronic lung diseases, and fibromyalgia each increase risk for taking substantial sick leave. Altogether, these results may help motivate improved diagnostic and treatment options for persons living with post-Covid conditions.
UR - http://www.scopus.com/inward/record.url?scp=85173635560&partnerID=8YFLogxK
U2 - 10.1038/s41467-023-42048-1
DO - 10.1038/s41467-023-42048-1
M3 - Journal article
C2 - 37805514
SN - 2041-1722
VL - 14
JO - Nature Communications
JF - Nature Communications
IS - 1
M1 - 6266
ER -