A homogeneous assay for analysis of FMR1 promoter methylation in patients with fragile X syndrome

Keyphrases

• Fragile X Syndrome 100%
• Fragile X Mental Retardation 1 (FMR1) 100%
• Gene Promoter Methylation 100%
• Homogeneous Assay 100%
• Male Donor 42%
• Melting Peak 42%
• Male Patients 28%
• Methylation 28%
• Melting Curve Analysis 28%
• CGG Trinucleotide Repeats 28%
• Southern Blot Analysis 28%
• Full mutation 28%
• Molecular Diagnostics 14%
• Healthy Males 14%
• Mutation Carriers 14%
• Mosaicism 14%
• Genomic DNA (gDNA) 14%
• Methylation Status 14%
• CpG Sites 14%
• CGG Repeat 14%
• Repeat Region 14%
• CpG Island 14%
• LightCycler 14%
• 5′-untranslated Region (5′-UTR) 14%
• Rapid Identification 14%
• Accurate Identification 14%
• Melting Curve 14%
• Hypermethylated 14%
• SYBR Green 14%
• Normal numbers 14%
• Repeat number 14%
• Sodium Bisulfite 14%
• Cellular Methylation 14%
• Low Melting 14%
• High-temperature Melting 14%
• Premutation 14%
• Gene Promoter Region 14%

Biochemistry, Genetics and Molecular Biology

• Methylation 100%
• Gene Promoter 100%
• Melting Point 80%
• Promoter Region 40%
• Trinucleotide Repeat Expansion 40%
• Southern Blotting 40%
• Melting Curve Analysis 40%
• Premutation 40%
• Mosaicism 20%
• Untranslated Region 20%
• CpG Site 20%
• CpG Island 20%
• Bisulfite 20%
• Sodium Bisulfite 20%
• SYBR Green I 20%
• Genomics 20%