TY - JOUR
T1 - A fragmented field
T2 - why ovarian biology needs dedicated integrative platforms
AU - Amorim, Christiani A.
AU - Williams, Suzannah A.
AU - Kristensen, Stine Gry
N1 - Publisher Copyright:
© The Author(s) 2026. Published by Oxford University Press on behalf of the Society for the Study of Reproduction. All rights reserved. For commercial re-use, please contact [email protected] for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact [email protected]. This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/pages/standard-publication-reuse-rights)
PY - 2026/7/15
Y1 - 2026/7/15
N2 - The ovary plays a central role in female reproductive and endocrine health, yet ovarian biology remains structurally fragmented across disciplines including reproductive medicine, endocrinology, toxicology, and bioengineering. This fragmentation limits the integration of mechanistic insights, slows clinical translation, and constrains our understanding of the ovary as a complex, multi-scale organ. Recent advances in technologies such as single-cell analysis, organoid systems, and biomaterials have generated unprecedented knowledge, but these developments often remain siloed. Here, we argue that advancing the field requires the establishment of dedicated integrative platforms that bridge basic, translational, and clinical research. Using recent interdisciplinary initiatives as a proof-of-concept, we propose key principles for such platforms and call for structural changes in how ovarian research is organized, supported, and disseminated.
AB - The ovary plays a central role in female reproductive and endocrine health, yet ovarian biology remains structurally fragmented across disciplines including reproductive medicine, endocrinology, toxicology, and bioengineering. This fragmentation limits the integration of mechanistic insights, slows clinical translation, and constrains our understanding of the ovary as a complex, multi-scale organ. Recent advances in technologies such as single-cell analysis, organoid systems, and biomaterials have generated unprecedented knowledge, but these developments often remain siloed. Here, we argue that advancing the field requires the establishment of dedicated integrative platforms that bridge basic, translational, and clinical research. Using recent interdisciplinary initiatives as a proof-of-concept, we propose key principles for such platforms and call for structural changes in how ovarian research is organized, supported, and disseminated.
KW - interdisciplinarity
KW - ovarian biology
KW - research infrastructure
KW - scientific integration
KW - systems biology
KW - translational research
UR - https://www.scopus.com/pages/publications/105044955023
U2 - 10.1093/biolre/ioag100
DO - 10.1093/biolre/ioag100
M3 - Review
C2 - 42133572
AN - SCOPUS:105044955023
SN - 0006-3363
VL - 115
SP - 1
EP - 4
JO - Biology of Reproduction
JF - Biology of Reproduction
IS - 1
ER -