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A EAACI drug allergy interest group survey on how European allergy specialists deal with β-lactam allergy

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

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  • Maria Jose Torres
  • Gulfem Elif Celik
  • Paul Whitaker
  • Marina Atanaskovic-Markovic
  • Annick Barbaud
  • Andreas Bircher
  • Miguel Blanca
  • Knut Brockow
  • Jean-Christoph Caubet
  • Josefina Rodrigues Cernadas
  • Anca Chiriac
  • Pascal Demoly
  • Lene Heise Garvey
  • Hans F Merk
  • Holger Mosbech
  • Alla Nakonechna
  • Antonino Romano
Vis graf over relationer

An accurate diagnosis of β-lactam (BL) allergy can reduce patient morbidity and mortality. Our aim was to investigate the availability of BL reagents, their use and test procedures in different parts of Europe, as well as any differences in the diagnostic workups for evaluating subjects with BL hypersensitivity. A survey was emailed to all members of the EAACI Drug Allergy Interest Group (DAIG) between February and April 2016, and the questionnaire was meant to study the management of suspected BL hypersensitivity. The questionnaire was emailed to 82 DAIG centres and answered by 57. Amoxicillin alone or combined to clavulanic acid were the most commonly involved BL except in the Danish centre, where penicillin V was the most frequently suspected BL. All centres performed an allergy workup in subjects with histories of hypersensitivity to BL: 53 centres (93%) followed DAIG guidelines, two national guidelines and two local guidelines. However, there were deviations from DAIG recommendations concerning allergy tests, especially drug provocation tests. A significant heterogeneity exists in current practice not only among countries, but also among centres within the same country. This suggests the need to re-evaluate, update and standardize protocols on the management of patients with suspected BL allergy.

OriginalsprogEngelsk
TidsskriftAllergy
Vol/bind74
Udgave nummer6
Sider (fra-til)1052-1062
Antal sider11
ISSN0105-4538
DOI
StatusUdgivet - jun. 2019

Bibliografisk note

© 2019 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

ID: 59001881