TY - JOUR
T1 - A Consensus Statement on the management of Vertebral Fractures in CKD stages G4-G5D
AU - Fusaro, Maria
AU - Chandran, Manju
AU - Nickolas, Thomas
AU - Ferrari, Serge
AU - Cossettini, Althea
AU - Ebeling, Peter R
AU - Closkey, Eugene Mc
AU - Harvey, Nicholas
AU - Pierroz, Dominque D
AU - Cannata-Andia, Jorge
AU - Cheung, Angela
AU - Guglielmi, Giuseppe
AU - Glüer, Claus
AU - Foldes, Joseph
AU - W, Lems
AU - Trombetti, Andrea
AU - Mithal, Ambrish
AU - Napoli, Nicola
AU - Haarhaus, Mathias
AU - Ferraro, Pietro Manuel
AU - Ketteler, Markus
AU - Bellasi, Antonio
AU - Moyses, Rosa
AU - Evenepoel, Pieter
AU - Jørgensen, Hanne Skou
AU - Reginster, Jean-Yves
AU - Halbout, Philippe
AU - Bover, Jordi
AU - Gallieni, Maurizio
AU - Salam, Syazrah
AU - Eastell, Richard
AU - Hansen, Ditte
AU - Cavalier, E
AU - Brandi, Maria L
N1 - © The Author(s) 2025. Published by Oxford University Press on behalf of the ERA.
PY - 2025/11/28
Y1 - 2025/11/28
N2 - Skeletal fragility has long been overlooked by the nephrology community, despite patients with chronic kidney disease (CKD) facing double the risk of hip fracture compared with the general population. Consequently, the term CKD-associated osteoporosis was recently coined to increase awareness. In this context, vertebral fractures are even less studied. Vertebral fractures predict increased fracture risk, and especially in advanced CKD show a strong association with aortic and iliac vascular calcifications, and cardiovascular events such as myocardial infarction. The scope of the present consensus paper is to comprehensively discuss the management of skeletal fragility in CKD patients, from diagnosis to treatment, with a particular focus on vertebral fractures in CKD G4-G5D.
AB - Skeletal fragility has long been overlooked by the nephrology community, despite patients with chronic kidney disease (CKD) facing double the risk of hip fracture compared with the general population. Consequently, the term CKD-associated osteoporosis was recently coined to increase awareness. In this context, vertebral fractures are even less studied. Vertebral fractures predict increased fracture risk, and especially in advanced CKD show a strong association with aortic and iliac vascular calcifications, and cardiovascular events such as myocardial infarction. The scope of the present consensus paper is to comprehensively discuss the management of skeletal fragility in CKD patients, from diagnosis to treatment, with a particular focus on vertebral fractures in CKD G4-G5D.
U2 - 10.1093/ndt/gfaf256
DO - 10.1093/ndt/gfaf256
M3 - Journal article
C2 - 41313307
SN - 0931-0509
JO - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
JF - Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
ER -