A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys

A Juul, K Sørensen, L Aksglaede, I Garn, E Rajpert-De Meyts, I Hullstein, P Hemmersbach, A M Ottesen

28 Citationer (Scopus)

Abstract

Testosterone (T) is excreted in urine as water-soluble glucuronidated and sulfated conjugates. The ability to glucuronidate T and other steroids depends on a number of different glucuronidases (UGT) of which UGT2B17 is essential. The aim of the study was to evaluate the influence of UGT2B17 genotypes on urinary excretion of androgen metabolites in pubertal boys.
OriginalsprogEngelsk
TidsskriftJournal of Clinical Endocrinology and Metabolism
Vol/bind94
Udgave nummer3
Sider (fra-til)1005-11
Antal sider7
ISSN0021-972X
DOI
StatusUdgivet - 2009

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