A 9-week randomized trial comparing a chronotherapeutic intervention (wake and light therapy) to exercise in major depressive disorder patients treated with duloxetine

Klaus Martiny, Else Refsgaard, Vibeke Lund, Marianne Lunde, Lene Sørensen, Britta Thougaard, Lone Lindberg, Per Bech

77 Citationer (Scopus)

Abstract

The onset of action of antidepressants often takes 4 to 6 weeks. The antidepressant effect of wake therapy (sleep deprivation) comes within hours but carries a risk of relapse. The objective of this study was to investigate whether a new chronotherapeutic intervention combining wake therapy with bright light therapy and sleep time stabilization could induce a rapid and sustained augmentation of response and remission in major depressive disorder.
OriginalsprogEngelsk
TidsskriftPrimary Care Companion to C N S Disorders
Vol/bind73
Udgave nummer9
Sider (fra-til)1234-42
Antal sider9
ISSN2155-7772
DOI
StatusUdgivet - 2012

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