A 7T interleaved fMRS and fMRI study on visual contrast dependency in the human brain

Anouk Schrantee, Chloe Najac, Chris Jungerius, Aart J Nederveen, Vincent Oltman Boer, Wietske van der Zwaag, Silvia Mangia, Itamar Ronen

Abstract

Functional magnetic resonance spectroscopy can non-invasively measure changes in local concentrations of neurometabolites and has been used to demonstrate changes in lactate and glutamate levels in response to visual stimulation. However, whether the neurometabolite response scales with the level of neuronal stimulation like the BOLD response, has not been extensively investigated. We here show that lactate, but not glutamate levels, change dependent on visual contrast levels (baseline, 10%, 100% contrast). Although we also demonstrate a significant contrast dependence in the BOLD response, we do not find a significant association between the lactate response and the BOLD response.
OriginalsprogEngelsk
TitelProceedings of the 2020 ISMRM & SMRT Virtual Conference & Exhibition
Antal sider1
ForlagThe International Society for Magnetic Resonance in Medicine
Publikationsdato2020
Sider1-1
Artikelnummer0489
StatusUdgivet - 2020
Begivenhed2020 ISMRM & SMRT Virtual Conference & Exhibition -
Varighed: 8 aug. 202014 aug. 2020
https://www.ismrm.org/20m/

Konference

Konference2020 ISMRM & SMRT Virtual Conference & Exhibition
Periode08/08/202014/08/2020
Internetadresse

Fingeraftryk

Dyk ned i forskningsemnerne om 'A 7T interleaved fMRS and fMRI study on visual contrast dependency in the human brain'. Sammen danner de et unikt fingeraftryk.

Citationsformater