(99m)Tc-aprotinin - optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis

Charlotte Denholt; Nic Gillings

doi:10.1002/jlcr.3381

(99m)Tc-aprotinin - optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis

Afdeling for Klinisk Fysiologi og Nuklearmedicin DIA

1 Citationer (Scopus)

Abstract

Technetium-99m aprotinin was prepared from an optimised radiolabelling kit formulation containing aprotinin, alkaline buffer and stannous chloride (reducing agent) and radiolabelled using (99m) Tc-pertechnetate. The labelling was achieved within 25 min, with radiochemical purities of >98%.

Originalsprog	Engelsk
Tidsskrift	Journal of Labelled Compounds and Radiopharmaceuticals
Vol/bind	59
Udgave nummer	4
Sider (fra-til)	171-4
Antal sider	4
ISSN	0362-4803
DOI	https://doi.org/10.1002/jlcr.3381
Status	Udgivet - apr. 2016

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10.1002/jlcr.3381

Citationsformater

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title = "(99m)Tc-aprotinin - optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis",

abstract = "Technetium-99m aprotinin was prepared from an optimised radiolabelling kit formulation containing aprotinin, alkaline buffer and stannous chloride (reducing agent) and radiolabelled using (99m) Tc-pertechnetate. The labelling was achieved within 25 min, with radiochemical purities of >98\%.",

keywords = "Amyloidosis, Aprotinin, Diagnostic Imaging, Isotope Labeling, Radiochemistry, Technetium, Journal Article",

author = "Charlotte Denholt and Nic Gillings",

note = "Copyright {\textcopyright} 2016 The Authors. Journal of Labelled Compounds and Radiopharmaceuticals published by John Wiley \& Sons, Ltd.",

year = "2016",

month = apr,

doi = "10.1002/jlcr.3381",

language = "English",

volume = "59",

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AU - Denholt, Charlotte

AU - Gillings, Nic

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N2 - Technetium-99m aprotinin was prepared from an optimised radiolabelling kit formulation containing aprotinin, alkaline buffer and stannous chloride (reducing agent) and radiolabelled using (99m) Tc-pertechnetate. The labelling was achieved within 25 min, with radiochemical purities of >98%.

AB - Technetium-99m aprotinin was prepared from an optimised radiolabelling kit formulation containing aprotinin, alkaline buffer and stannous chloride (reducing agent) and radiolabelled using (99m) Tc-pertechnetate. The labelling was achieved within 25 min, with radiochemical purities of >98%.

KW - Amyloidosis

KW - Aprotinin

KW - Diagnostic Imaging

KW - Isotope Labeling

KW - Radiochemistry

KW - Technetium

KW - Journal Article

U2 - 10.1002/jlcr.3381

DO - 10.1002/jlcr.3381

M3 - Journal article

C2 - 26923297

SN - 0362-4803

VL - 59

SP - 171

EP - 174

JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

IS - 4

ER -

(99m)Tc-aprotinin - optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis

Abstract

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