Abstract
Background and aims The role of 5 aminosalicylic acid (5 ASA) in Crohns disease is unclear The outcome of the first course of 5 ASA monotherapy with emphasis on 5 ASA dependency was retrospectively assessed in consecutive cohort of 537 Crohn s disease patients diagnosed 1953-2007 Methods Following outcome definitions were used Immediate outcome (30 days after 5-ASA start) defined as complete/partial response (total regression/improvement of symptoms) and no response (no regression of symptoms with a need of corticosteroids, immunomodulator or surgery) Long term outcome defined as prolonged response (still in complete/partial response 1 year after induction of response), 5 ASA dependency (relapse on stable/reduced dose of 5 ASA requiring dose escalation to regain response or relapse
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Journal of Crohn's and Colitis |
| Vol/bind | 4 |
| Udgave nummer | 5 |
| Sider (fra-til) | 575-581 |
| Antal sider | 7 |
| ISSN | 1873-9946 |
| Status | Udgivet - 2010 |