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12-year survival analysis of 322 Hintegra total ankle arthroplasties from an independent center

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@article{459bfa4d271c476c928376874c334f07,
title = "12-year survival analysis of 322 Hintegra total ankle arthroplasties from an independent center",
abstract = "Background and purpose - Total ankle arthroplasties (TAAs) have larger revision rates than hip and knee implants. We examined the survival rates of our primary TAAs, and what different factors, including the cause of arthritis, affect the success and/or revision rate.Patients and methods - From 2004 to 2016, 322 primary Hintegra TAAs were implanted: the 2nd generation implant from 2004 until mid-2007 and the 3rd generation from late 2007 to 2016. A Cox proportional hazards model evaluated sex, age, primary diagnosis, and implant generation, pre- and postoperative angles and implant position as risk factors for revision.Results - 60 implants (19{\%}) were revised, the majority (n = 34) due to loosening. The 5-year survival rate (95{\%} CI) was 75{\%} (69-82) and the 10-year survival rate was 68{\%} (60-77). There was a reduced risk of revision, per degree of increased postoperative medial distal tibial angle at 0.84 (0.72-0.98) and preoperative talus angle at 0.95 (0.90-1.00), indicating that varus ankles may have a larger revision rate. Generation of implant, sex, primary diagnosis, and most pre- and postoperative radiological angles did not statistically affect revision risk.Interpretation - Our revision rates are slightly above registry rates and well above those of the developer. Most were revised due to loosening; no difference was demonstrated with the 2 generations of implant used. Learning curve and a low threshold for revision could explain the high revision rate.",
author = "Zafar, {Mina Jane} and Thomas Kallemose and Mostafa Benyahia and Ebskov, {Lars Bo} and Penny, {Jeannette {\O}stergaard}",
year = "2020",
month = "8",
doi = "10.1080/17453674.2020.1751499",
language = "English",
volume = "91",
pages = "444--449",
journal = "Acta Orthopaedica (Online)",
issn = "1745-3682",
publisher = "Taylor & Francis Ltd",
number = "4",

}

RIS

TY - JOUR

T1 - 12-year survival analysis of 322 Hintegra total ankle arthroplasties from an independent center

AU - Zafar, Mina Jane

AU - Kallemose, Thomas

AU - Benyahia, Mostafa

AU - Ebskov, Lars Bo

AU - Penny, Jeannette Østergaard

PY - 2020/8

Y1 - 2020/8

N2 - Background and purpose - Total ankle arthroplasties (TAAs) have larger revision rates than hip and knee implants. We examined the survival rates of our primary TAAs, and what different factors, including the cause of arthritis, affect the success and/or revision rate.Patients and methods - From 2004 to 2016, 322 primary Hintegra TAAs were implanted: the 2nd generation implant from 2004 until mid-2007 and the 3rd generation from late 2007 to 2016. A Cox proportional hazards model evaluated sex, age, primary diagnosis, and implant generation, pre- and postoperative angles and implant position as risk factors for revision.Results - 60 implants (19%) were revised, the majority (n = 34) due to loosening. The 5-year survival rate (95% CI) was 75% (69-82) and the 10-year survival rate was 68% (60-77). There was a reduced risk of revision, per degree of increased postoperative medial distal tibial angle at 0.84 (0.72-0.98) and preoperative talus angle at 0.95 (0.90-1.00), indicating that varus ankles may have a larger revision rate. Generation of implant, sex, primary diagnosis, and most pre- and postoperative radiological angles did not statistically affect revision risk.Interpretation - Our revision rates are slightly above registry rates and well above those of the developer. Most were revised due to loosening; no difference was demonstrated with the 2 generations of implant used. Learning curve and a low threshold for revision could explain the high revision rate.

AB - Background and purpose - Total ankle arthroplasties (TAAs) have larger revision rates than hip and knee implants. We examined the survival rates of our primary TAAs, and what different factors, including the cause of arthritis, affect the success and/or revision rate.Patients and methods - From 2004 to 2016, 322 primary Hintegra TAAs were implanted: the 2nd generation implant from 2004 until mid-2007 and the 3rd generation from late 2007 to 2016. A Cox proportional hazards model evaluated sex, age, primary diagnosis, and implant generation, pre- and postoperative angles and implant position as risk factors for revision.Results - 60 implants (19%) were revised, the majority (n = 34) due to loosening. The 5-year survival rate (95% CI) was 75% (69-82) and the 10-year survival rate was 68% (60-77). There was a reduced risk of revision, per degree of increased postoperative medial distal tibial angle at 0.84 (0.72-0.98) and preoperative talus angle at 0.95 (0.90-1.00), indicating that varus ankles may have a larger revision rate. Generation of implant, sex, primary diagnosis, and most pre- and postoperative radiological angles did not statistically affect revision risk.Interpretation - Our revision rates are slightly above registry rates and well above those of the developer. Most were revised due to loosening; no difference was demonstrated with the 2 generations of implant used. Learning curve and a low threshold for revision could explain the high revision rate.

UR - http://www.scopus.com/inward/record.url?scp=85083874266&partnerID=8YFLogxK

U2 - 10.1080/17453674.2020.1751499

DO - 10.1080/17453674.2020.1751499

M3 - Journal article

VL - 91

SP - 444

EP - 449

JO - Acta Orthopaedica (Online)

JF - Acta Orthopaedica (Online)

SN - 1745-3682

IS - 4

ER -

ID: 59663016