1. trimester-screening for præeklampsi

Iben Riishede; Martin Overgaard; Henriette Ladegård Skov; Puk Sandager; Ann Tabor; Line Rode; Charlotte Kvist Ekelund

doi:10.61409/V11240762

1. trimester-screening for præeklampsi

Iben Riishede, Martin Overgaard, Henriette Ladegård Skov, Puk Sandager, Ann Tabor, Line Rode, Charlotte Kvist Ekelund

Abstract

Pre-eclampsia is a common and serious pregnancy complication. This review describes that low-dose acetylsalicylic acid can reduce the risk of preterm pre-eclampsia in high-risk pregnant women if treatment is started before the 16th week of pregnancy. A new screening algorithm can already, in the first trimester of pregnancy, predict an individual woman's risk of developing pre-eclampsia by combining a series of biophysical and biochemical markers with maternal risk factors. The screening has been validated internationally and in Denmark. In 2025, a national implementation project will be initiated to evaluate the effectiveness of a change in screening strategy in Denmark.

Bidragets oversatte titel	First-trimester screening for pre-eclampsia
Originalsprog	Dansk
Artikelnummer	V11240762
Tidsskrift	Ugeskrift for Laeger
Vol/bind	187
Udgave nummer	18
ISSN	0041-5782
DOI	https://doi.org/10.61409/V11240762
Status	Udgivet - 28 apr. 2025

Emneord

Humans
Pregnancy
Female
Pre-Eclampsia/diagnosis
Pregnancy Trimester, First
Aspirin/administration & dosage
Risk Factors
Biomarkers/blood
Mass Screening/methods
Algorithms
Denmark

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10.61409/V11240762Licens: CC BY-NC-ND

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Citationsformater

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abstract = "Pre-eclampsia is a common and serious pregnancy complication. This review describes that low-dose acetylsalicylic acid can reduce the risk of preterm pre-eclampsia in high-risk pregnant women if treatment is started before the 16th week of pregnancy. A new screening algorithm can already, in the first trimester of pregnancy, predict an individual woman's risk of developing pre-eclampsia by combining a series of biophysical and biochemical markers with maternal risk factors. The screening has been validated internationally and in Denmark. In 2025, a national implementation project will be initiated to evaluate the effectiveness of a change in screening strategy in Denmark.",

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AU - Riishede, Iben

AU - Overgaard, Martin

AU - Skov, Henriette Ladegård

AU - Sandager, Puk

AU - Tabor, Ann

AU - Rode, Line

AU - Ekelund, Charlotte Kvist

N1 - Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.

PY - 2025/4/28

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N2 - Pre-eclampsia is a common and serious pregnancy complication. This review describes that low-dose acetylsalicylic acid can reduce the risk of preterm pre-eclampsia in high-risk pregnant women if treatment is started before the 16th week of pregnancy. A new screening algorithm can already, in the first trimester of pregnancy, predict an individual woman's risk of developing pre-eclampsia by combining a series of biophysical and biochemical markers with maternal risk factors. The screening has been validated internationally and in Denmark. In 2025, a national implementation project will be initiated to evaluate the effectiveness of a change in screening strategy in Denmark.

AB - Pre-eclampsia is a common and serious pregnancy complication. This review describes that low-dose acetylsalicylic acid can reduce the risk of preterm pre-eclampsia in high-risk pregnant women if treatment is started before the 16th week of pregnancy. A new screening algorithm can already, in the first trimester of pregnancy, predict an individual woman's risk of developing pre-eclampsia by combining a series of biophysical and biochemical markers with maternal risk factors. The screening has been validated internationally and in Denmark. In 2025, a national implementation project will be initiated to evaluate the effectiveness of a change in screening strategy in Denmark.

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KW - Pregnancy

KW - Female

KW - Pre-Eclampsia/diagnosis

KW - Pregnancy Trimester, First

KW - Aspirin/administration & dosage

KW - Risk Factors

KW - Biomarkers/blood

KW - Mass Screening/methods

KW - Algorithms

KW - Denmark

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U2 - 10.61409/V11240762

DO - 10.61409/V11240762

M3 - Review

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VL - 187

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

IS - 18

M1 - V11240762

ER -

1. trimester-screening for præeklampsi

Abstract

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