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Region Hovedstaden - en del af Københavns Universitetshospital

The Copenhagen Child Cohort 2000 studies (Martin Køster Rimvall PhD thesis and other studies)

Projekt: Typer af projekterProjekt

  • Jeppesen, Pia (Projektleder, faglig)
  • Rimvall, Martin (Projektdeltager)
  • Skovgaard, Anne Mette (Projektdeltager)
  • Olsen, Else Marie (Projektdeltager)
  • Linneberg, Allan (Projektdeltager)
  • Larsen, Michael (Projektdeltager)
  • Rask, Charlotte U. (Projektdeltager)
  • Os, Jim van, Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Centre Utrecht, Utrecht, The Netherlands; Department of Psychiatry and Psychology, Maastricht University Medical Centre, Maastricht, The Netherlands; Department of Psychosis Studies, King's College London, King's Health Partners, Institute of Psychiatry, London, UK., Holland (Samarbejdspartner)
  • Verhulst, Frank, Department of Child Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, The Netherlands., Holland (Samarbejdspartner)
Vis graf over relationer
The Copenhagen Child Cohort (CCC2000) is a longitudinal birth cohort with a unique dataset for investigation of the epidemiology of developmental psychopathology from infancy onwards. By repeated linkage of the database to data drawn from the Danish national registries at Statistics Denmark, we can continue to study a broad range of correlates and outcomes of psychopathology prospectively from birth.
We study the developmental trajectories to psychosis in the CCC2000. The studies are based on a dimensional approach to measures of psychopathology. Within this framework, psychosis is seen on a continuum ranging from subclinical psychotic experiences (PE) that are common in the general population to manifest psychotic disorders at the severe end of the spectrum. The psychosis study group have mapped the correlates and outcomes of PE at age 11 years (interview-based) and at age 16 years (self-reported) in the CCC2000. Our results have shown that PE in childhood are strong risk-markers of concurrent and later emotional and neurodevelopmental disorders, suicidality, poor quality of life, health anxiety and functional physical symptoms, even after adjustment for general psychopathology.
So far, the CCC2000 study lacked power to study the incidence of manifest psychotic disorder as a function of PE, however this will be a highly relevant outcome to study as the young individuals enter the peak age of onset and diagnosis of psychotic disorders.
StatusIgangværende
Periode01/10/201701/10/2020

    Forskningsområder

  • Sundhedsvidenskab - Behavioral, emotional disorders onset child/adolescence, Mood Disorders, Neurodevelopmental Disorders, Schizophrenia Spectrum and Other Psychotic Disorders, Somatoform Disorders, Substance-Related Disorders, Trauma and Stressor Related Disorders, including traumatic experience in childhood, Suicide, Phenomenology, Epidemiologic, Biomarkers, Registerbased research, Psychological assessment and psychometrics, Observational Study

ID: 61971518