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Region Hovedstaden - en del af Københavns Universitetshospital

Rumination-focused Cognitive Behaviour Therapy for non-responsive depression: Case-series

Projekt: Typer af projekterProjekt

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The purpose of this case-series is to investigate the feasibility and effect of individual RfCBT for patients with treatment non-responsive depression. The target population is patients diagnosed with major depression (F32-33) that have received pharmacological treatment for a minimum of 12 months and are currently depressed. Twelve patients with depression will be recruited from and treated within an outpatient service in Denmark. Primary outcome is HAM-D-17. Secondary outcomes include changes in rumination/worry, well-being, and social functioning.The treatment consists of 12 individual sessions of RfCBT conducted over a period of 4 months. A three-month follow up for primary and secondary outcomes is planned. Patients will also be assessed weekly through treatment on clinical measures. It is hoped that this case series will provide insight and information into the feasibility and effect of individual RfCBT for people that are suffering from depression that has been non-responsive to other treatment and is chronic in nature.


  • Sundhedsvidenskab - Rumination-focused Cognitive Behaviour Therapy, Chronic treatment resistant depression, Rumination, Psychotherapy, Mood Disorders, Randomized Controlled Clinical Trial

ID: 46012157