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Region Hovedstaden - en del af Københavns Universitetshospital

Psychopsysiological profiling of attentional deficits in children with psychosis or ADHD?/Do adolescents with psychotic symptoms show early indicators of schizophrenia?

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There is a great need to identify early indicators of the disease in populations at high risk for schizophrenia. An obvious group at high risk for developing schizophrenia is young adolescents with psychosis, since psychosis is such a central feature in schizophrenia. It is known from a five year follow-up study performed in our research group that approximately 30 % of adolescents who experience a first episode of psychosis at a later stage developed schizophrenia. From another recent study in our group, it is known that first-episode, antipsychotic naïve schizophrenia patients show a large number of psychophysiological and neurocognitive deficits. The current project is therefore designed to investigate whether a subgroup can be identified among
adolescents with a first episode of psychotic disorder showing the same psychophysiological and/or neurocognitive deficits as are previously found in our first-episode, antipsychotic naïve schizophrenia patients. It will be determined if the presence of these deficits can predict who of the subjects will develop schizophrenia within a period of 5 years. The data of these subjects will be compared to a group of healthy control subjects and a group of first-episode schizophrenia patients, both in the same age range. The project will give valuable information in the search for strategies aimed at identifying and eventually preventing adolescents with a psychotic episode to develop schizophrenia later in life.
StatusAfsluttet
Periode01/02/201030/10/2015
FinansieringskildeIntern støtte (Offentlig)
ForskningsprogramRegion Hovedstadens Psykiatri Forskningspulje
Beløb1.530.000,00 Danske Kroner
Årstal2011

ID: 32195241