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Region Hovedstaden - en del af Københavns Universitetshospital

Internet-based Cognition Assessment Tool: development and validation of a novel online screening tool for cognitive impairment (ICAT)

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Intro:
Internet-based Cognition Assessment Tool: development and validation of a novel online screening tool for cognitive impairment (2018-Present). There is a need for objective neuropsychological tools to screen for cognitive impairment in participants to avoid inclusion of objectively “cognitively intact” patients and hence type 2 errors in cognition trials. Development of an internet-based objective cognition screening tool for assessment of candidate participants at home before face-to-face screenings would represent an immense methodological advancement. Such tools will also enable unprecedented large-scale assessment of objective cognitive abilities and its association with mental health and occupational functioning in nationwide, register-based studies. We therefore set up a collaboration with researchers at the Danish Technical University (DTU) to create and test such a new internet-based test, the Internet-based Cognition Assessment Tool (ICAT).
Metoder:
Observational study involving one assessment of remitted patients with bipolar disorder and healthy controls with an internet-based cognition screening tool, Internet-based Cognition Assessment Tool (ICAT), a neuropsychological test battery and a clinical rating of mood symptoms.
Resultater (forventede):
Patients displayed cognitive impairments compared to controls on the ICAT. There was a strong correlation between ICAT and the standard cognition measure, SCIP total score and moderate to strong correlations on subtest scores. Across all participants, lower ICAT scores correlated with more subjective cognitive complaints and poorer psychosocial functioning. In conclusion, the ICAT is a sensitive and valid web-based tool to assess cognitive impairments in remitted patients with bipolar disorder.
Diskussion/Impact (forventet):
The findings highlight the ICAT as a feasible web-based cognition screener that can be easily implemented to facilitate assessment and monitoring of cognitive impairments in the clinical management of bipolar disorder.

The resulting paper is currently “in review”
StatusIgangværende
Periode01/01/201801/01/2025

    Forskningsområder

  • Sundhedsvidenskab - Mood Disorders, Psychological assessment and psychometrics, Cognition, Observational study

ID: 61746356