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Region Hovedstaden - en del af Københavns Universitetshospital

CAVIR (part 1)

Projekt: Typer af projekterProjekt

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Cognition Assessment in Virtual Reality: Validity and feasibility of a novel virtual reality test for real-life cognitive functions in affective and psychotic disorders (2019-Present). There is a pressing need for measures of real-life cognitive functioning in patients with affective or psychotic disorders as well as methods for training cognition in virtual reality. We therefore developed the first immersive virtual reality cognition assessment tool, the Cognition Assessment Virtual Reality (CAVIR), which assesses verbal memory, processing speed, sustained attention, working memory and planning skills in a 360⁰ kitchen scenario. We also developed a prototype of a cognitive training scenario in another 360⁰ kitchen scenario. In the first part of the study, we investigated the sensitivity and validity of the CAVIR for cognitive impairments in affective and psychotic disorders and its association with functional capacity and neuropsychological performance. In the second part, we investigated the feasibility and efficacy of cognitive training in virtual reality.
Observational validation study (part 1 of the study) and a pilot RCT to examine the feasibility and efficacy of cognitive training in virtual reality (part 2).
In part 1, we assessed 40 patients with affective disorders, 41 patients with psychosis spectrum disorders and 40 healthy controls with the CAVIR, a battery of neuropsychological tests, functional assessment and mood ratings.
In part 2, we randomized a total of 42 patients with either affective or psychosis spectrum disorders to receive three training sessions over a week with a novel virtual reality training scenario or treatment as usual. All participants underwent CAVIR and neuropsychological testing and mood ratings at baseline and after one week.
Resultater (forventede):
We found that the CAVIR is a valid and sensitive measure of cognitive impairments in affective and psychosis spectrum disorders (Miskowiak et al, in review) and that virtual reality training over one week was feasible and improved their cognitive functions in daily life (paper in prep.)

The resulting paper from part 1 is currently “in review”, while the paper from part 2 is “in prep”


  • Sundhedsvidenskab - Mood Disorders, Psychotherapy, Psychological assessment and psychometrics, Cognition, Observational study

ID: 61746683