Thomas Frandsen

Publikation

Publikationer pr. år 1997 2014 2015 2016 2017 2018 2020 2021 2022 2023

• 66 Tidsskriftartikel
• 5 Review
• 1 Letter
• 1 Andet bidrag

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2023

  Gastrointestinal barrier integrity and mucosal inflammation as risk factors of blood stream infections in children treated for acute lymphoblastic leukaemia

  De Pietri, S., Weischendorff, S., Rathe, M., Frandsen, T. L., Hasle, H., Nersting, J., Nielsen, C. H., Moser, C. & Müller, K., 1 nov. 2023, I: International Journal of Cancer. 153, 9, s. 1635-1642 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Inflammation 59%
  • Infections 48%
  • Citrulline 48%
  • Child 44%

• Markers of neutrophil chemotaxis for identification of blood stream infections in children with acute lymphoblastic leukemia undergoing induction treatment

  Weischendorff, S., De Pietri, S., Rathe, M., Frandsen, T. L., Hasle, H., Nielsen, C. H., Moser, C. & Müller, K., jun. 2023, I: European Journal of Haematology. 110, 6, s. 762-771 10 s.

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  • Chemotaxis 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 91%
  • Neutrophils 73%
  • Infections 44%
  • Child 40%
• 2022

  Asparaginase Enzyme Activity Levels and Toxicity in Childhood Acute Lymphoblastic Leukemia: a NOPHO ALL2008 study

  Lynggaard, L. S., Rank, C. U., Hansen, S. N., Gottschalk Højfeldt, S., Henriksen, L. T., Jarvis, K. B., Ranta, S., Niinimäki, R., Harila-Saari, A., Wolthers, B. O., Frandsen, T. L., Heyman, M., Schmiegelow, K. & Albertsen, B. K., 11 jan. 2022, I: Blood advances. 6, 1, s. 138-147 10 s.

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  • Asparaginase 100%
  • Hematology 78%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 71%
  • Pediatrics 47%
  • Enzymes 40%

• Can Machine Learning Models Predict Asparaginase-associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia

  Nielsen, R. L., Wolthers, B. O., Helenius, M., Albertsen, B. K., Clemmensen, L., Nielsen, K., Kanerva, J., Niinimäki, R., Frandsen, T. L., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Aytan-Aktug, D., Liu, H-C., Möricke, A., Samarasinghe, S., van der Sluis, I. M., Stanulla, M., Tulstrup, M., & 4 flereYadav, R., Zapotocka, E., Schmiegelow, K. & Gupta, R., 1 apr. 2022, I: Journal of Pediatric Hematology/Oncology. 44, 3, s. e628-e636 9 s., 0000000000002292.

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  • Asparaginase 100%
  • Machine Learning 82%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 71%
  • Pancreatitis 71%
  • Single Nucleotide Polymorphism 27%
  2 Citationer (Scopus)

• Endothelial dysfunction and thromboembolism in children, adolescents, and young adults with acute lymphoblastic leukemia

  Andrés-Jensen, L., Grell, K., Rank, C. U., Albertsen, B. K., Tuckuviene, R., Linnemann Nielsen, R., Lynggaard, L. S., Jarvis, K. B., Quist-Paulsen, P., Trakymiene, S. S., Semaškevičienė, R., Saks, K., Jonsson, O. G., Frandsen, T. L., Johansson, P. I. & Schmiegelow, K., feb. 2022, I: Leukemia. 36, 2, s. 361-369 9 s.

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  • Thrombomodulin 100%
  • Thromboembolism 85%
  • Vascular Endothelial Growth Factor Receptor-1 74%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 74%
  • Young Adult 61%

• Rehabilitation Including Structured Active Play for Preschoolers With Cancer (RePlay)-Study Protocol for a Randomized Controlled Trial

  Pouplier, A., Winther, H., Christensen, J., Schmidt-Andersen, P., Zhang, H., Frandsen, T. L., Schmiegelow, K., Fridh, M. K. & Larsen, H. B., 2022, I: Frontiers in Pediatrics. 10, s. 1-11 11 s., 834512.

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  • Rehabilitation 100%
  • Randomized Controlled Trials 87%
  • Motor Skills 76%
  • Child 56%
  • Control Groups 52%

• Whole blood long-chain n-3 fatty acids as a measure of fish oil compliance in children with acute lymphoblastic leukemia: a pilot study

  Laumann, R. D., Iversen, T., Frandsen, T. L., Mølgaard, C., Stark, K. D., Schmiegelow, K. & Lauritzen, L., feb. 2022, I: Prostaglandins, leukotrienes, and essential fatty acids. 177, s. 102401 102401.

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  • Fish Oils 100%
  • Compliance 97%
  • Omega-3 Fatty Acids 89%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 79%
  • Fatty Acid 65%
• 2021

  Citrulline as a biomarker of bacteraemia during induction treatment for childhood acute lymphoblastic leukaemia

  De Pietri, S., Frandsen, T. L., Christensen, M., Grell, K., Rathe, M. & Müller, K., jan. 2021, I: Pediatric Blood & Cancer. 68, 1, s. e28793 e28793.

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  • Citrulline 100%
  • Bacteremia 78%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 75%
  • Biomarkers 50%
  • Neutrophils 34%
  10 Citationer (Scopus)

• Effect of Fish Oil Supplementation on Hyperlipidemia during Childhood Acute Lymphoblastic Leukemia Treatment - A Pilot Study

  Laumann, R. D., Iversen, T., Mogensen, P. R., Lauritzen, L., Mølgaard, C. & Frandsen, T. L., 2021, I: Nutrition and Cancer. 73, 9, s. 1816-1820 5 s.

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  • Fish Oils 100%
  • Hyperlipidemias 81%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 79%
  • Osteonecrosis 37%
  • Pancreatitis 31%

• Increments in DNA-thioguanine level during thiopurine enhanced maintenance therapy of acute lymphoblastic leukemia

  Larsen, R. H., Utke Rank, C., Grell, K., Nørgaard Møller, L., Malthe Overgaard, U., Kampmann, P., Nersting, J., Degn, M., Nygaard Nielsen, S., Holst, H., Klug Albertsen, B., Skov Wehner, P., Thude Callesen, M., Kanerva, J., Leth Frandsen, T., Als-Nielsen, B., Lyngsie Hjalgrim, L. & Schmiegelow, K., 1 nov. 2021, I: Haematologica. 106, 11, s. 2824-2833 10 s.

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  • Thioguanine 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 70%
  • DNA 40%
  • Methotrexate 26%
  • purine 25%

• Maintenance therapy and risk of osteonecrosis in children and young adults with acute lymphoblastic leukemia: a NOPHO ALL2008 sub-study

  Toksvang, L. N., Andrés-Jensen, L., Rank, C. U., Niinimäki, R., Nersting, J., Nielsen, S. N., Mogensen, S. S., Harila-Saari, A., Abrahamsson, J., Joelsson, J., Overgaard, U. M., Quist-Paulsen, P., Griškevičius, L., Jónsson, Ó. G., Vaitkevičienė, G., Frandsen, T. L., Toft, N., Grell, K. & Schmiegelow, K., nov. 2021, I: Cancer Chemotherapy and Pharmacology. 88, 5, s. 911-917 7 s.

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  • Methotrexate 100%
  • Osteonecrosis 92%
  • Mercaptopurine 85%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 78%
  • Young Adult 64%
  4 Citationer (Scopus)

• National, clinical cohort study of late effects among survivors of acute lymphoblastic leukaemia: the ALL-STAR study protocol

  Andrés-Jensen, L., Skipper, M. T., Mielke Christensen, K., Hedegaard Johnsen, P., Aagaard Myhr, K., Kaj Fridh, M., Grell, K., Pedersen, A. M. L., Leisgaard Mørck Rubak, S., Ballegaard, M., Hørlyck, A., Beck Jensen, R., Lambine, T-L., Gjerum Nielsen, K., Tuckuviene, R., Skov Wehner, P., Klug Albertsen, B., Schmiegelow, K. & Frandsen, T. L., 9 feb. 2021, I: BMJ Open. 11, 2, s. 1-12 12 s., e045543.

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  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Survivors 89%
  • Clinical Studies 70%
  • Cohort Studies 69%
  • Denmark 54%
  2 Citationer (Scopus)

• Relapse risk following truncation of pegylated asparaginase in childhood acute lymphoblastic leukemia

  Gottschalk Højfeldt, S., Grell, K., Abrahamsson, J., Lund, B., Vettenranta, K., Jonsson, O. G., Frandsen, T. L., Wolthers, B. O., Marquart, H. V. H., Vaitkeviciene, G., Lepik, K., Heyman, M., Schmiegelow, K. & Albertsen, B. K., 29 apr. 2021, I: Blood. 137, 17, s. 2373-2382 10 s.

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  • pegaspargase 100%
  • Asparaginase 77%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 55%
  • Enzyme Activity 46%
  • Recurrence 32%

• TPMT polymorphisms and minimal residual disease after 6-mercaptopurine post-remission consolidation therapy of childhood acute lymphoblastic leukaemia

  Dreisig, K., Brünner, E. D., Marquart, H. V., Helt, L. R., Nersting, J., Frandsen, T. L., Jonsson, O. G., Taskinen, M., Vaitkeviciene, G., Lund, B., Abrahamsson, J., Lepik, K. & Schmiegelow, K., apr. 2021, I: Pediatric Hematology and Oncology. 38, 3, s. 227-238 12 s.

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  • thiopurine methyltransferase 100%
  • Mercaptopurine 86%
  • Residual Neoplasm 68%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 63%
  • Genotype 18%
  3 Citationer (Scopus)
• 2020

  Asparaginase-Associated Pancreatitis in Acute Lymphoblastic Leukemia: Results From the NOPHO ALL2008 Treatment of Patients 1-45 Years of Age

  Rank, C. U., Wolthers, B. O., Grell, K., Albertsen, B. K., Frandsen, T. L., Overgaard, U. M., Toft, N., Nielsen, O. J., Wehner, P. S., Harila-Saari, A., Heyman, M. M., Malmros, J., Abrahamsson, J., Norén-Nyström, U., Tomaszewska-Toporska, B., Lund, B., Jarvis, K. B., Quist-Paulsen, P., Vaitkevičienė, G. E., Griškevičius, L., & 6 flereTaskinen, M., Wartiovaara-Kautto, U., Lepik, K., Punab, M., Jónsson, Ó. G. & Schmiegelow, K., 1 jan. 2020, I: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 38, 2, s. 145-154 10 s.

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  • Asparaginase 100%
  • Hematology 78%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 71%
  • Pancreatitis 71%
  • Pediatrics 47%
  39 Citationer (Scopus)

• Bovine Colostrum Against Chemotherapy-Induced Gastrointestinal Toxicity in Children With Acute Lymphoblastic Leukemia: A Randomized, Double-Blind, Placebo-Controlled Trial

  Rathe, M., De Pietri, S., Wehner, P. S., Frandsen, T. L., Grell, K., Schmiegelow, K., Sangild, P. T., Husby, S. & Müller, K., feb. 2020, I: Journal of Parenteral and Enteral Nutrition. 44, 2, s. 337-347 11 s.

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  • Colostrum 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 72%
  • Cattle 59%
  • Placebos 50%
  • Fever 46%
  23 Citationer (Scopus)

• Dyslipidemia at diagnosis of childhood acute lymphoblastic leukemia

  Mogensen, P. R., Grell, K., Schmiegelow, K., Overgaard, U. M., Wolthers, B. O., Mogensen, S. S., Vaag, A. & Frandsen, T. L., 6 apr. 2020, I: PLoS One. 15, 4, e0231209.

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  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Dyslipidemias 99%
  • Thromboembolism 43%
  • Hypercholesterolemia 38%
  • Hypertriglyceridemia 29%
  10 Citationer (Scopus)

• Effects of a physical activity program from diagnosis on cardiorespiratory fitness in children with cancer: a national non-randomized controlled trial

  Nielsen, M. K. F., Christensen, J. F., Frandsen, T. L., Thorsteinsson, T., Andersen, L. B., Christensen, K. B., Wehner, P. S., Hasle, H., Adamsen, L. Ø., Schmiegelow, K. & Larsen, H. B., 6 jul. 2020, I: BMC Medicine. 18, 1, s. 1-12 12 s., 175.

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  • Cardiorespiratory Fitness 100%
  • Non-Randomized Controlled Trials 89%
  • Exercise 50%
  • Child 33%
  • Neoplasms 24%

• Everyday life challenges among adolescent and young adult survivors of childhood acute lymphoblastic leukemia: An in-depth qualitative study

  Andrés-Jensen, L., Larsen, H. B., Johansen, C., Frandsen, T. L., Schmiegelow, K. & Wahlberg, A., okt. 2020, I: Psycho-Oncology. 29, 10, s. 1630-1637 8 s.

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  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • young adult 85%
  • everyday life 84%
  • Young Adult 82%
  • childhood 69%
  18 Citationer (Scopus)

• Flow cytometric detection of leukemic blasts in cerebrospinal fluid predicts risk of relapse in childhood acute lymphoblastic leukemia: a Nordic Society of Pediatric Hematology and Oncology study

  Thastrup, M., Marquart, H. V., Levinsen, M., Grell, K., Abrahamsson, J., Albertsen, B. K., Frandsen, T. L., Harila-Saari, A., Lähteenmäki, P. M., Niinimäki, R., Pronk, C. J., Ulvmoen, A., Vaitkevičienė, G., Taskinen, M., Schmiegelow, K. & Nordic Society of Pediatric Hematology and Oncology (NOPHO), feb. 2020, I: Leukemia. 34, 2, s. 336-346 11 s.

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  • Hematology 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 91%
  • Cerebrospinal Fluid 81%
  • Pediatrics 60%
  • Recurrence 53%
  42 Citationer (Scopus)

• Gastrointestinal toxicity during induction treatment for childhood acute lymphoblastic leukemia: The impact of the gut microbiota

  De Pietri, S., Ingham, A. C., Frandsen, T. L., Rathe, M., Krych, L., Castro-Mejía, J. L., Nielsen, D. S., Nersting, J., Wehner, P. S., Schmiegelow, K., Hasle, H., Pamp, S. J. & Müller, K., 1 okt. 2020, I: International Journal of Cancer. 147, 7, s. 1953-1962 10 s.

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  • Enterocytes 100%
  • Gastrointestinal Microbiome 83%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 83%
  • Citrulline 82%
  • C-Reactive Protein 56%

• T-cell acute lymphoblastic leukemia in patients 1-45 years treated with the pediatric NOPHO ALL2008 protocol

  Quist-Paulsen, P., Toft, N., Heyman, M., Abrahamsson, J., Griškevičius, L., Hallböök, H., Jónsson, Ó. G., Palk, K., Vaitkeviciene, G., Vettenranta, K., Åsberg, A., Frandsen, T. L., Opdahl, S., Marquart, H. V., Siitonen, S., Osnes, L. T., Hultdin, M., Overgaard, U. M., Wartiovaara-Kautto, U. & Schmiegelow, K., feb. 2020, I: Leukemia. 34, 2, s. 347-357 11 s.

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  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Pediatrics 48%
  • Residual Neoplasm 20%
  • Age Groups 13%
  • Asparaginase 12%
  30 Citationer (Scopus)
• 2019

  Hepatotoxicity during 6-thioguanine treatment in inflammatory bowel disease and childhood acute lymphoblastic leukaemia: A systematic review

  Toksvang, L. N., Schmidt, M. S., Arup, S., Larsen, R. H., Frandsen, T. L., Schmiegelow, K. & Rank, C. U., 24 maj 2019, I: PLoS One. 14, 5, s. e0212157

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  • Thioguanine 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 70%
  • Inflammatory Bowel Diseases 67%
  • Systematic Reviews 52%
  • Hyperplasia 19%

• Insulin-dependent diabetes: A chronic complication to acute pancreatitis in childhood acute lymphoblastic leukemia

  Wolthers, B. O., Mogensen, P. R., Frandsen, T. L., Abrahamsson, J., Behrendtz, M., Heyman, M., Lohi, O., Norén-Nyström, U., Ruud, E. & Schmiegelow, K., 1 jan. 2019, I: Pediatric Blood & Cancer. 66, 1, s. e27437

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  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Pancreatitis 99%
  • Insulin 69%
  • Pancreatic Pseudocyst 35%
  • Asparaginase 34%
  9 Citationer (Scopus)

• Intermittent Versus Continuous PEG-Asparaginase to Reduce Asparaginase-Associated Toxicities: A NOPHO ALL2008 Randomized Study

  Albertsen, B. K., Grell, K., Abrahamsson, J., Lund, B., Vettenranta, K., Jónsson, Ó. G., Frandsen, T. L., Wolthers, B. O., Heyman, M. & Schmiegelow, K., 2019, I: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37, 19, s. 1638-1646 9 s.

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  • pegaspargase 100%
  • Asparaginase 77%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 41%
  • Pancreatitis 41%
  • Osteonecrosis 33%

• Trypsin-encoding PRSS1-PRSS2 variations influence the risk of asparaginase-associated pancreatitis in children with acute lymphoblastic leukemia: a Ponte di Legno toxicity working group report

  Wolthers, B. O., Frandsen, T. L., Patel, C. J., Abaji, R., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Grosjean, M., Krajinovic, M., Larsen, E., Liang, D-C., Möricke, A., Rasmussen, K. K., Samarasinghe, S., Silverman, L. B., van der Sluis, I. M., Stanulla, M., Tulstrup, M., Yadav, R., & 4 flereYang, W., Zapotocka, E., Gupta, R. & Schmiegelow, K., 2019, I: Haematologica. 104, 3, s. 556-563 8 s.

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  • Asparaginase 100%
  • Trypsin 74%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 71%
  • Pancreatitis 71%
  • Child 31%
  27 Citationer (Scopus)
• 2018

  Association between body mass index and pancreatitis in children with acute lymphoblastic leukemia

  Mogensen, P. R., Wolthers, B. O., Grell, K., Schmiegelow, K. & Frandsen, T. L., aug. 2018, I: Pediatric Blood & Cancer. 65, 8, s. e27071

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• Comparing osteonecrosis clinical phenotype, timing, and risk factors in children and young adults treated for acute lymphoblastic leukemia

  Mogensen, S. S., Retpen, J., Helt, L. R., Toft, N., Schmiegelow, K., Frandsen, T. L. & Nordic Society of Paediatric Haematology and Oncology (NOPHO) group, okt. 2018, I: Pediatric Blood & Cancer. 65, 10, s. e27300

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  • Osteonecrosis 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 84%
  • Young Adult 69%
  • Phenotype 51%
  • Child 37%
  31 Citationer (Scopus)

• Individualized 6-mercaptopurine increments in consolidation treatment of childhood acute lymphoblastic leukemia: A NOPHO randomized controlled trial

  Tulstrup, M., Frandsen, T. L., Abrahamsson, J., Lund, B., Vettenranta, K., Jonsson, O. G., Marquart, H. V. H., Albertsen, B. K., Heyman, M. & Schmiegelow, K., 2018, I: European Journal of Haematology. 100, 1, s. 53-60 8 s.

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  • Mercaptopurine 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 73%
  • Randomized Controlled Trials 50%
  • Residual Neoplasm 31%
  • Progression-Free Survival 27%
  6 Citationer (Scopus)

• Putative new childhood leukemia cancer predisposition syndrome caused by germline bi-allelic missense mutations in DDX41

  Diness, B. R., Risom, L., Frandsen, T. L., Hansen, B., Andersen, M. K., Schmiegelow, K. & Wadt, K. A. W., 2018, I: Genes, Chromosomes & Cancer. 57, 12, s. 670-674

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  • Missense Mutation 100%
  • Leukemia 79%
  • Mutation 54%
  • Exome 46%
  • RNA Sequence Analysis 43%
  11 Citationer (Scopus)

• Results of NOPHO ALL2008 treatment for patients aged 1-45 years with acute lymphoblastic leukemia

  Toft, N., Birgens, H., Abrahamsson, J., Griškevičius, L., Hallböök, H., Heyman, M., Klausen, T. W., Jónsson, Ó. G., Palk, K., Pruunsild, K., Quist-Paulsen, P., Vaitkeviciene, G., Vettenranta, K., Åsberg, A., Frandsen, T. L., Marquart, H. V., Madsen, H. O., Norén-Nyström, U. & Schmiegelow, K., 2018, I: Leukemia. 32, s. 606-15

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  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Leukemia 27%
  • Cranial Irradiation 23%
  • Remission Induction 22%
  • Philadelphia Chromosome 21%
  251 Citationer (Scopus)

• Role of TPMT and ITPA variants in mercaptopurine disposition

  Gerbek, T., Ebbesen, M., Nersting, J., Frandsen, T. L., Appell, M. L. & Schmiegelow, K., mar. 2018, I: Cancer Chemotherapy and Pharmacology. 81, 3, s. 579-586 8 s.

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  • inosine triphosphatase 100%
  • Thiopurine 91%
  • Mercaptopurine 91%
  • thiopurine methyltransferase 85%
  • Inosine 69%

• Testing physical function in children undergoing intense cancer treatment-a RESPECT feasibility study

  Nielsen, M. K. F., Christensen, J. F., Frandsen, T. L., Thorsteinsson, T., Andersen, L. B., Christensen, K. B., Nersting, J., Faber, M., Schmiegelow, K. & Larsen, H. B., aug. 2018, I: Pediatric Blood & Cancer. 65, 8, s. e27100

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  • Feasibility Studies 100%
  • Child 41%
  • Neoplasms 30%
  • Exercise Test 23%
  • Leukemia 19%

• The cost of cure

  Schmiegelow, K. & Frandsen, T. L., nov. 2018, I: The Lancet. Haematology. 5, 11, s. e504-e505

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• Thromboembolism in acute lymphoblastic leukemia: results of NOPHO ALL2008 protocol treatment in patients aged 1 to 45 years

  Rank, C. U., Toft, N., Tuckuviene, R., Grell, K., Nielsen, O. J., Frandsen, T. L., Marquart, H. V. H., Albertsen, B. K., Tedgård, U., Hallböök, H., Ruud, E., Jarvis, K. B., Quist-Paulsen, P., Huttunen, P., Wartiovaara-Kautto, U., Jónsson, Ó. G., Trakymiene, S. S., Griškevičius, L., Saks, K., Punab, M., & 1 flereSchmiegelow, K., 31 maj 2018, I: Blood. 131, 22, s. 2475-2484 10 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Thromboembolism 100%
  • Clinical Protocols 88%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 86%
  • Confidence Intervals 52%
  • carboxyimamidate 16%
  71 Citationer (Scopus)

• Treatment-related mortality in relapsed childhood acute lymphoblastic leukemia

  Oskarsson, T., Söderhäll, S., Arvidson, J., Forestier, E., Frandsen, T. L., Hellebostad, M., Lähteenmäki, P., Jónsson, Ó. G., Myrberg, I. H., Heyman, M. & Nordic Society of Paediatric Haematology and Oncology (NOPHO) ALL Relapse Working Group, 2018, I: Pediatric Blood and Cancer. 65, 4, s. e26909

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Mortality 51%
  • Recurrence 26%
  • Hematopoietic Stem Cell Transplantation 19%
  • Therapeutics 16%
  22 Citationer (Scopus)
• 2017

  Asparaginase-associated pancreatitis: a study on phenotype and genotype in the NOPHO ALL2008 protocol

  Wolthers, B. O., Frandsen, T. L., Abrahamsson, J., Albertsen, B. K., Helt, L. R., Heyman, M., Jónsson, Ó. G., Kõrgvee, L. T., Lund, B., Raja, R. A., Rasmussen, K. K., Taskinen, M., Tulstrup, M., Vaitkevičienė, G. E., Yadav, R., Gupta, R. & Schmiegelow, K., feb. 2017, I: Leukemia. 31, 2, s. 325-332 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Asparaginase 100%
  • Pancreatitis 71%
  • Genotype 52%
  • Phenotype 44%
  • Odds Ratio 11%
  51 Citationer (Scopus)

• Asparaginase-associated pancreatitis in childhood acute lymphoblastic leukaemia: an observational Ponte di Legno Toxicity Working Group study

  Wolthers, B. O., Frandsen, T. L., Baruchel, A., Attarbaschi, A., Barzilai, S., Colombini, A., Escherich, G., Grell, K., Inaba, H., Kovacs, G., Liang, D-C., Mateos, M., Mondelaers, V., Möricke, A., Ociepa, T., Samarasinghe, S., Silverman, L. B., van der Sluis, I. M., Stanulla, M., Vrooman, L. M., & 4 flereYano, M., Zapotocka, E., Schmiegelow, K. & Ponte di Legno Toxicity Working Group, sep. 2017, I: Lancet Oncology. 18, 9, s. 1238-1248 11 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Asparaginase 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 71%
  • Pancreatitis 71%
  • Abdominal Pain 16%
  • Insulin 15%
  72 Citationer (Scopus)

• Asparaginase-associated pancreatitis is not predicted by hypertriglyceridemia or pancreatic enzyme levels in children with acute lymphoblastic leukemia

  Raja, R. A., Schmiegelow, K., Sørensen, D. N. & Frandsen, T. L., jan. 2017, I: Pediatric Blood and Cancer. 64, 1, s. 32-38 7 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Asparaginase 100%
  • Hypertriglyceridemia 83%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 71%
  • Pancreatitis 71%
  • Enzymes 40%
  21 Citationer (Scopus)

• Early presentation of osteonecrosis in acute lymphoblastic leukemia: Two children from the Nordic and Baltic cohort

  Mogensen, S. S., Harila-Saari, A., Frandsen, T. L., Lähteenmäki, P., Castor, A., Kohonen, I., Schmiegelow, K. & Mäkitie, O., nov. 2017, I: Pediatric Blood and Cancer. 64, 11, s. e26624

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  • Osteonecrosis 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 84%
  • Child 37%
  • Knee 13%
  • Pediatrics 11%
  6 Citationer (Scopus)

• Hepatic sinusoidal obstruction syndrome during maintenance therapy of childhood acute lymphoblastic leukemia is associated with continuous asparaginase therapy and mercaptopurine metabolites

  Toksvang, L. N., De Pietri, S., Nielsen, S. N., Nersting, J., Albertsen, B. K., Wehner, P. S., Rosthøj, S., Lähteenmäki, P. M., Nilsson, D., Nystad, T. A., Grell, K., Frandsen, T. L. & Schmiegelow, K., sep. 2017, I: Pediatric Blood and Cancer. 64, 9, s. e26519

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Hepatic Veno-Occlusive Disease 100%
  • pegaspargase 90%
  • Asparaginase 88%
  • Mercaptopurine 86%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 63%
  17 Citationer (Scopus)

• Hyperlipidemia is a risk factor for osteonecrosis in children and young adults with acute lymphoblastic leukemia

  Mogensen, S. S., Schmiegelow, K., Grell, K., Albertsen, B. K., Wehner, P. S., Kampmann, P. & Frandsen, T. L., maj 2017, I: Haematologica. 102, 5, s. e175-e178

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  38 Citationer (Scopus)

• Prolonged first-line PEG-asparaginase treatment in pediatric acute lymphoblastic leukemia in the NOPHO ALL2008 protocol-Pharmacokinetics and antibody formation

  Tram Henriksen, L., Gottschalk Højfeldt, S., Schmiegelow, K., Frandsen, T. L., Skov Wehner, P., Schrøder, H., Klug Albertsen, B. & Nordic Society of Pediatric Hematology and Oncology, NOPHO Group, dec. 2017, I: Pediatric Blood and Cancer. 64, 12, s. e26686

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • pegaspargase 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 55%
  • Asparaginase 54%
  • Antibody Formation 51%
  • Pharmacokinetics 42%
  25 Citationer (Scopus)

• Successful Treatment of Rhino-Orbital-Cerebral Mucormycosis in a Child With Leukemia

  Jensen, T. S. R., Arendrup, M. C., Buchwald, C. V., Frandsen, T. L., Juhler, M. & Nygaard, U., 2017, I: Journal of Pediatric Hematology / Oncology. 39, 4, s. e211-e215

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mucormycosis 100%
  • Amphotericin B 80%
  • Leukemia 59%
  • posaconazole 34%
  • Terbinafine 33%
  15 Citationer (Scopus)
• 2016

  Consensus definitions of 14 severe acute toxic effects for childhood lymphoblastic leukaemia treatment: a Delphi consensus

  Schmiegelow, K., Attarbaschi, A., Barzilai, S., Escherich, G., Frandsen, T. L., Halsey, C., Hough, R., Jeha, S., Kato, M., Liang, D-C., Mikkelsen, T. S., Möricke, A., Niinimäki, R., Piette, C., Putti, M. C., Raetz, E., Silverman, L. B., Skinner, R., Tuckuviene, R., van der Sluis, I., & 2 flereZapotocka, E. & Ponte di Legno toxicity working group, jun. 2016, I: Lancet Oncology. 17, 6, s. e231-9

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Consensus 96%
  • Poisons 75%
  • Asparaginase 30%
  • Methotrexate 21%
  164 Citationer (Scopus)

• Leukemic blasts are present at low levels in spinal fluid in one-third of childhood acute lymphoblastic leukemia cases

  Levinsen, M., Marquart, H. V., Groth-Pedersen, L., Abrahamsson, J., Albertsen, B. K., Andersen, M. K., Frandsen, T. L., Harila-Saari, A., Pronk, C., Ulvmoen, A., Vaitkevičienė, G., Lähteenmäki, P. M., Niinimäki, R., Taskinen, M., Jeppesen, M., Schmiegelow, K. & Nordic Society of Pediatric Hematology and Oncology (NOPHO), nov. 2016, I: Pediatric Blood and Cancer. 63, 11, s. 1935-42 8 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Flow Cytometry 77%
  • Cerebrospinal Fluid 55%
  • Cell Biology 44%
  • Central Nervous System 18%
  33 Citationer (Scopus)

• Measures of 6-mercaptopurine and methotrexate maintenance therapy intensity in childhood acute lymphoblastic leukemia

  Nielsen, S. N., Grell, K., Nersting, J., Frandsen, T. L., Hjalgrim, L. L. & Schmiegelow, K., nov. 2016, I: Cancer Chemotherapy and Pharmacology. 78, 5, s. 983-994 12 s.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Mercaptopurine 100%
  • Methotrexate 93%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 73%
  • Nucleotide 51%
  • Lymphocyte Count 47%
  28 Citationer (Scopus)

• Parents' and Adolescents' Preferences for Intensified or Reduced Treatment in Randomized Lymphoblastic Leukemia Trials

  Tulstrup, M., Larsen, H. B., Castor, A., Rossel, P., Grell, K., Heyman, M., Abrahamsson, J., Söderhäll, S., Åsberg, A., Jonsson, O. G., Vettenranta, K., Frandsen, T. L., Albertsen, B. K., Schmiegelow, K. & Nordic Society of Paediatric Haematology, and Oncology (NOPHO), 31 dec. 2016, I: Pediatric Blood & Cancer. 63, 5, s. 865-71

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  • Mercaptopurine 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 85%
  • Asparaginase 85%
  • Parents 65%
  • Vincristine 54%
  8 Citationer (Scopus)

• Test and validation of methods to sample and detect human virus from environmental surfaces using norovirus as a model virus

  Ibfelt, T., Frandsen, T., Permin, A., Andersen, L. P. & Schultz, A. C., apr. 2016, I: The Journal of hospital infection. 92, 4, s. 378-84 7 s.

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  • Norovirus 100%
  • Viruses 51%
  • Polyesters 48%
  • Mengovirus 44%
  • Multiplex Polymerase Chain Reaction 14%
  8 Citationer (Scopus)

• Toxicity profile and treatment delays in NOPHO ALL2008-comparing adults and children with Philadelphia chromosome-negative acute lymphoblastic leukemia

  Toft, N., Birgens, H., Abrahamsson, J., Griškevičius, L., Hallböök, H., Heyman, M., Klausen, T. W., Jónsson, Ó. G., Palk, K., Pruunsild, K., Quist-Paulsen, P., Vaitkeviciene, G., Vettenranta, K., Asberg, A., Helt, L. R., Frandsen, T. & Schmiegelow, K., 13 apr. 2016, I: European Journal of Haematology. 96, 2, s. 160-9

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  • Philadelphia Chromosome 100%
  • Time-to-Treatment 86%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 76%
  • Osteonecrosis 36%
  • Child 33%
  48 Citationer (Scopus)