Personlig profil
Expertise
My expertise is performing genetic analysis on sparse and/or degraded material. I undertake the daily molecular analysis of biomarkers / somatic mutations relevant for the diagnosis and treatment of a wide variety of cancers.
"Primære forskningsområder
My research interests are implementation and development of diagnostic tests for biomarkers relevant for a wide range of oncological diseases and Creutzfeldt-Jakob disease (CJD). I am also involved in projects aiming at identifying new diagnostic and prognostic markers in cancer.
"Aktuel forskning
CJD, Glioblastoma, pilocytic astrocytoma, RNA fusions, mtDNA, NGS, Neuroendocrine tumors.
Mulige interessekonflikter
No conflict of interest
Fingeraftryk
- 1 Lignende profiler
Samarbejde og topforskningsområder i de sidste fem år
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Novel insights into meningioma brain invasion with spatial transcriptomic profiling
Maier, A. D., Laurentiussen, C. O., Michaelsen, S. R., Perino, L., Stannius, T. O., Harwood, D. S. L., Klausen, M. N., Haslund-Vinding, J., Bager, N. S., Scheie, D., Schmidt, A. Y., Melchior, L. C., Areškevičiūtė, A., Vilhardt, F., Josefsen, K. E., Raleigh, D. R., Bagger, F. O., Mathiesen, T. & Kristensen, B. W., 4 jan. 2026, I: Acta neuropathologica communications. 14, 1, 17 s., 32.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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PRRX1-rearranged Fibroblastic Tumors: A Clinicopathologic and Molecular Study of 18 Cases Including a Novel PRRX1::EP300 Fusion
Dehner, C. A., Torres-Mora, J., Thangaiah, J. J., Oliveira, A., Michal, M., Malik, F., Din, N. U., Hassan, U., Maqbool, H., Obeidin, F., Caragea, M., Lee, C.-H., Schubart, C., Agaimy, A., Grundtmann, B., Melchior, L., Talman, M.-L., Gross, J., Cheah, A. L. & Thway, K. & 3 flere, , 1 jan. 2026, I: American Journal of Surgical Pathology. 50, 1, s. 31-40 10 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Actionable alterations in glioblastoma: Insights from the implementation of genomic profiling as the standard of care from 2016 to 2023
Fougner, V., Urup, T., Poulsen, H. S., Grunnet, K., Westmose, C. Y., Melchior, L. C., Larsen, K. B., Højgaard, M., Spanggaard, I., Belcaid, L., Rohrberg, K. S., Lassen, U., Hasselbalch, B. & Nørøxe, D. S., feb. 2025, I: Neuro-Oncology Practice. 12, 1, s. 34-44 11 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
3 Citationer (Scopus) -
Clinical, Radiological, and Molecular Insights into Extracranial Metastases from Adult Gliomas
Jacobsen, J., Locallo, A., O'Rourke, C. J., Carlsen, J. F., Cohen, J., Ewald, J. D., Scheie, D., Grunnet, K., Schmidt, A. Y., Melchior, L. C., Larsen, V. A., Andersen, J. B., Poulsen, H. S., Weischenfeldt, J., Broholm, H., Michaelsen, S. R. & Kristensen, B. W., 16 aug. 2025, (E-pub ahead of print) I: Neuro-Oncology.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Improvement of Diagnostics in NSCLC Patients with MET Exon 14 Mutations Using Complementary DNA/RNA-NGS and Identification of Two Novel Exonic Splicing Mutations
Urbanska, E. M., Doktor, T. K., Melchior, L. C., Petersson, E. S., Sørensen, J. B., Santoni-Rugiu, E., Andresen, B. S. & Grauslund, M., 22 dec. 2025, I: International Journal of Molecular Sciences. 27, 1, 106.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review