Hematology; Oncology; Acute Myeloid Leukemia, Stem Cell Biology; AML mouse models; Flow Cytometry;
Deciphering the molecular and cellular components of the blood-forming organ; Regulation of hematopoietic stem cell self-renewal and differentiation, Understanding the pathogenesis of hematological malignancies.
Identification of small molecule inhibitors targeting aberrant signaling and metabolism in cancer stem cells in AML mouse models and patient-derived xenograft models.
Identification of human hematopoietic stem cells markers for improved cell therapies of cancer patients.
Development of immunotherapy approaches for acute myeloid leukemia.