Cellular based assays.

Endocytic receptors; Collagen receptors; Interaction between cells and extracellular matrix.

I am working to identify biologically relevant ligands of an endocytic receptor, know to play important role in fibrosis and certain cancers. I am working on a mass spectrometry-based proteomics screen aiming at identifying unknown ligands taken up by this receptor in vitro and in vivo. Methods will include several techniques within cell biology, molecular biology and protein chemistry as well as work with mice to clarify protein function in vivo.