Personlig profil
Expertise
- Acute myeloid leukemia. (AML).
- Hematology
Primære forskningsområder
- Mapping of clonal hierarchies in patients with acute myeloid leukemia (AML).
- Identification and therapeutic targeting of oncogenic signaling pathways in AML.
- Application of "omics" technologies to improve prediction of therapy response in patients with AML.
Aktuel forskning
The major focus of the laboratory´s translational research program is to compare cancer cells to their closest normal cellular counterpart using a variety of “omics” technologies in order to improve prognostication as well as identify novel targets such as for treatment of patients with acute myeloid leukemia (AML).
Mulige interessekonflikter
None.
Fingeraftryk
- 1 Lignende profiler
Samarbejde og topforskningsområder i de sidste fem år
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The glycosaminoglycan oncofetal chondroitin sulfate is a novel target for antibody-drug conjugate therapy for AML
Mujollari, J., Estruch Alrich, M., Khadgawat, P., Choudhary, S., Gustavsson, T., Dagil, R., Redlinger, N., Løppke, C., Vidal Calvo, E., Anemone Nordmaj, M., Theander, T. G., Heidenreich, O., Nguyen, Y., Qin, S., Tølbøll Sørensen, A. L., Grønbæk, K., Porse, B. T., Kircher, B., Mueller, J. & Agerbæk, M. & 2 flere, , 12 mar. 2026, I: Blood. 147, 11, s. 1229-1236 8 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
1 Citationer (Scopus) -
Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics
Furtwängler, B., Üresin, N., Richter, S., Schuster, M. B., Barmpouri, D., Holze, H., Wenzel, A., Grønbæk, K., Theilgaard-Mönch, K., Theis, F. J., Schoof, E. M. & Porse, B. T., 16 okt. 2025, I: Science (New York, N.Y.). 390, 6770, s. eadr8785 eadr8785.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
10 Citationer (Scopus) -
Dose-reduction trials in oncology - aiming for less toxicity and better quality of life at lower costs
Theilgaard-Mönch, K. & Ehlers, L. H., feb. 2024, I: Nature Reviews Clinical Oncology. 21, 2, s. 81-82 2 s.Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning › peer review
3 Citationer (Scopus) -
Endomucin marks quiescent long-term multi-lineage repopulating hematopoietic stem cells and is essential for their transendothelial migration
Engelhard, S., Estruch, M., Qin, S., Engelhard, C. A., Rodriguez-Gonzalez, F. G., Drilsvik, M., Martin-Gonzalez, J., Lu, J.-W., Bryder, D., Nerlov, C., Weischenfeldt, J., Reckzeh, K. & Theilgaard-Mönch, K., 23 jul. 2024, I: Cell reports. 43, 7, 114475.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
6 Citationer (Scopus) -
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia
Kuusanmäki, H., Dufva, O., Vähä-Koskela, M., Leppä, A.-M., Huuhtanen, J., Vänttinen, I. M., Nygren, P. J., Klievink, J., Bouhlal, J. O. V., Pölönen, P., Zhang, Q., Adnan Awad, S., Mancebo-Pérez, C., Saad, J., Miettinen, J. J., Javarappa, K. K., Aakko, S., Ruokoranta, T., Eldfors, S. & Heinäniemi, M. & 9 flere, , 30 mar. 2023, I: Blood. 141, 13, s. 1610-1625 16 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
102 Citationer (Scopus)