Current position:

-Senior Scientist, Copenhagen Hepatitis C Program (CO-HEP) at Copenhagen University Hospital, Hvidovre

-Associate Professor in Experimental Control of Hepatitis C Virus, Faculty of Health and Medical Sciences at University of Copenhagen

Scientific focus areas:

In vitro studies of hepatitis C virus sensitivity and resistance to antivirals.

Hepatitis C virus vaccine development.

Development of hepatitis C virus cell culture systems.

Education:

2001: Doctoral degree (Dr. med.) at Ruprecht-Karls-University Heidelberg

1994-2001: Studies of Medicine, MD, Ruprecht-Karls-University Heidelberg                                         Fellowship of the German National Academic Foundation

Practical Professional Education:

09/2005 - present: Senior scientist, CO-HEP, Copenhagen University Hospital, Hvidovre, Copenhagen, Denmark.

11/2004 - 08/2005: Research and Clinical Associate, Department of Internal Medicin, University Hospital Bonn, Germany.

02/2003 - 08/2004: Clinical Associate, Department of Internal Medicine, Spital Limmattal, Zurich, Switzerland.

01/2002 - 01/2003: Research Associate, Department of Neuropathology, University Hospital, Zurich, Switzerland.        .

09/1997- 10/1998: Research fellowship at the Department of Pathology, Case Western, Reserve University, Cleveland, USA.

Contact: judith@gottwein.eu

HCV virology; HCV cell culture development; Study of antiviral compounds; HCV vaccine development; Cell culture; Molecular biology; Medicine

Main research areas are studies of resistance of HCV to antivirals and HCV vaccine development with focus on whole virus inactivated and virus like particle vaccine candidates.

We are characterizing the efficacy of antivirals and combinations of antivirals against different HCV variants. We further study HCV resistance to antivirals including identification of resistance associated substitutions and mechanisms of resistance development.

We investigate development of HCV vaccine candidates. We are establishing a bioprocess for development of whole viral particle inactivated vaccine candidates. We are testing such vaccine candidates and vaccine candidates based on virus like particles.

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