A screening method to spot biomarkers that may warn of serious events in a chronic disease - illustrated by cardiological CLARICOR trial data

Winkel, P., Hilden, J., Jakobsen, J. C., Lindschou, J., Jensen, G. B., Kjøller, E., Sajadieh, A., Kastrup, J., Kolmos, H. J., Larsson, A., Ärnlöv, J., Bjerre, M. & Gluud, C., 12 aug. 2021, (E-pub ahead of print) I: Clinical Chemistry and Laboratory Medicine.

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Proteoglycan Remodeling Is Accelerated in Females with Angina Pectoris and Diffuse Myocardial Fibrosis: the iPOWER Study

Mygind, N. D., Nielsen, S. H., Michelsen, M. M., Pena, A., Bechsgaard, D. F., Suhrs, E., Bove, K. B., Genovese, F., Nielsen, H. B., Karsdal, M., Vejlstrup, N., Prescott, E. & Kastrup, J., 1 mar. 2021, (E-pub ahead of print) I: Journal of Cardiovascular Translational Research.

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Coronary flow velocity reserve predicts adverse prognosis in women with angina and no obstructive coronary artery disease: results from the iPOWER study

Schroder, J., Michelsen, M. M., Mygind, N. D., Suhrs, H. E., Bove, K. B., Bechsgaard, D. F., Aziz, A., Gustafsson, I., Kastrup, J. & Prescott, E., 14 jan. 2021, I: European Heart Journal. 42, 3, s. 228-239 12 s.

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Impaired coronary flow velocity reserve is associated with cardiovascular risk factors but not with angina symptoms

Bove, K. B., Michelsen, M. M., Schroder, J., Suhrs, H. E., Bechsgaard, D. F., Mygind, N. D., Aziz, A., Kastrup, J., Gustafsson, I. & Prescott, E., jan. 2021, I: Open Heart. 8, 1, e001486.

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"Myocardial CT perfusion compared with transthoracic Doppler echocardiography in evaluation of the coronary microvascular function: An iPOWER substudy"

Bechsgaard, D. F., Hove, J. D., Michelsen, M. M., Mygind, N. D., Pena, A., Hansen, P. R., Hansen, H. S., Kastrup, J., Høst, N., Gustafsson, I. & Prescott, E., jan. 2021, I: Clinical Physiology and Functional Imaging. 41, 1, s. 85-94 10 s.

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Safety and feasibility of mesenchymal stem cell therapy in patients with aqueous deficient dry eye disease

Møller-Hansen, M., Larsen, A-C., Toft, P. B., Lynggaard, C. D., Schwartz, C., Bruunsgaard, H., Haack-Sørensen, M., Ekblond, A., Kastrup, J. & Heegaard, S., jan. 2021, I: The ocular surface. 19, s. 43-52 10 s.

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Efficacy and Mode of Action of Mesenchymal Stem Cells in Non-Ischemic Dilated Cardiomyopathy: A Systematic Review

Hoeeg, C., Frljak, S., Qayyum, A. A., Vrtovec, B., Kastrup, J., Ekblond, A. & Follin, B., 5 dec. 2020, I: Biomedicines. 8, 12

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Vaskulær endotelial vækstfaktor-terapi ved iskæmisk hjertesygdom.

Qayyum, A. A., Joshi, F. R., Lund, L. D., Søndergaard, R. H. & Kastrup, J., 26 okt. 2020, I: Ugeskrift for Laeger. 182, 44

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The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: the BAMI trial

BAMI Group, 7 okt. 2020, I: European Heart Journal. 41, 38, s. 3702-3710 9 s.

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Prognostic value of 12 novel cardiological biomarkers in stable coronary artery disease. A 10-year follow-up of the placebo group of the Copenhagen CLARICOR trial

Winkel, P., Jakobsen, J. C., Hilden, J., Jensen, G. B., Kjøller, E., Sajadieh, A., Kastrup, J., Kolmos, H. J., Iversen, K. K., Bjerre, M., Larsson, A., Ärnlöv, J. & Gluud, C., 20 aug. 2020, I: BMJ Open. 10, 8, e033720.

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The emergence of regenerative medicine in organ transplantation: 1st European Cell Therapy and Organ Regeneration Section meeting

Hoogduijn, M. J., Montserrat, N., van der Laan, L. J. W., Dazzi, F., Perico, N., Kastrup, J., Gilbo, N., Ploeg, R. J., Roobrouck, V., Casiraghi, F., Johnson, C. L., Franquesa, M., Dahlke, M. H., Massey, E., Hosgood, S. & Reinders, M. E. J., aug. 2020, I: Transplant international : official journal of the European Society for Organ Transplantation. 33, 8, s. 833-840 8 s.

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Inflammation, non-endothelial dependent coronary microvascular function and diastolic function-Are they linked?

Suhrs, H. E., Schroder, J., Bové, K. B., Mygind, N. D., Frestad, D., Michelsen, M. M., Lange, T., Gustafsson, I., Kastrup, J. & Prescott, E., 16 jul. 2020, I: PLoS One. 15, 7, e0236035.

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Bone marrow-derived mesenchymal stromal cell treatment in patients with ischaemic heart failure: final 4-year follow-up of the MSC-HF trial

Mathiasen, A. B., Qayyum, A. A., Jørgensen, E., Helqvist, S., Kofoed, K. F., Haack-Sørensen, M., Ekblond, A. & Kastrup, J., maj 2020, I: European Journal of Heart Failure. 22, 5, s. 884-892 9 s.

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Serum osteoprotegerin as a long-term predictor for patients with stable coronary artery disease and its association with diabetes and statin treatment: A CLARICOR trial 10-year follow-up substudy

Bjerre, M., Hilden, J., Winkel, P., Jensen, G. B., Kjøller, E., Sajadieh, A., Kastrup, J., Kolmos, H. J., Larsson, A., Ärnlöv, J., Jakobsen, J. C. & Gluud, C., maj 2020, I: Atherosclerosis. 301, s. 8-14 7 s.

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Prognosis and Reclassification by YKL-40 in Stable Coronary Artery Disease

Schroder, J., Jakobsen, J. C., Winkel, P., Hilden, J., Jensen, G. B., Sajadieh, A., Larsson, A., Ärnlöv, J., Harutyunyan, M., Johansen, J. S., Kjøller, E., Gluud, C. & Kastrup, J., 3 mar. 2020, I: Journal of the American Heart Association. 9, 5, s. e014634

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Pregnancy Associated Plasma Protein-A as a Cardiovascular Risk Marker in Patients with Stable Coronary Heart Disease During 10 Years Follow-Up-A CLARICOR Trial Sub-Study

Nilsson, E., Kastrup, J., Sajadieh, A., Boje Jensen, G., Kjøller, E., Kolmos, H. J., Wuopio, J., Nowak, C., Larsson, A., Jakobsen, J. C., Winkel, P., Gluud, C., Iversen, K. K., Ärnlöv, J. & Carlsson, A. C., 18 jan. 2020, I: Journal of Clinical Medicine. 9, 1

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Adipose Tissue-Derived Stromal Cells Induce a Highly Trophic Environment While Reducing Maturation of Monocyte-Derived Dendritic Cells

Juhl, M., Follin, B., Gad, M., Larsen, J., Kastrup, J. & Ekblond, A., 2020, I: Stem Cells International. 2020, s. 8868909

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Cardiac Magnetic Resonance Imaging used for Evaluation of Adipose-Derived Stromal Cell Therapy in Patients with Chronic Ischemic Heart Disease

Qayyum, A. A., Mathiasen, A. B., Mygind, N. D., Vejlstrup, N. G. & Kastrup, J., 1 dec. 2019, I: Cell Transplantation. 28, 12, s. 1700-1708

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Autologous adipose-derived stromal cell treatment for patients with refractory angina (MyStromalCell Trial): 3-years follow-up results

Qayyum, A. A., Mathiasen, A. B., Helqvist, S., Jørgensen, E., Haack-Sørensen, M., Ekblond, A. & Kastrup, J., 12 nov. 2019, I: Journal of Translational Medicine. 17, 1, s. 360

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Pro-inflammatory biomarkers in women with non-obstructive angina pectoris and coronary microvascular dysfunction

Schroder, J., Mygind, N. D., Frestad, D., Michelsen, M., Suhrs, H. E., Bove, K. B., Gustafsson, I., Kastrup, J. & Prescott, E., sep. 2019, I: International journal of cardiology. Heart & vasculature. 24, s. 100370

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Myocardial first pass perfusion assessed by cardiac magnetic resonance and coronary microvascular dysfunction in women with angina and no obstructive coronary artery disease

Mygind, N. D., Pena, A., Mide Michelsen, M., Ali Qayyum, A., Frestad, D., Emil Christensen, T., Ali Ghotbi, A., Hasbak, P., Kjaer, A., Vejlstrup, N., Prescott, E., Gustafsson, I., Riis Hansen, P., Steen Hansen, H. & Kastrup, J., jul. 2019, I: Scandinavian Journal of Clinical and Laboratory Investigation. 79, 4, s. 238-246 9 s.

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Coronary microvascular dysfunction is associated with cardiac time intervals in women with angina and no obstructive coronary artery disease: An iPOWER substudy

Pena, A., Michelsen, M. M., Mygind, N. D., Gustafsson, I., Høst, N., Bech, J., Kastrup, J., Hansen, H. S., Hansen, P. R. & Prescott, E., 1 jun. 2019, I: Echocardiography (Mount Kisco, N.Y.). 36, 6, s. 1110-1117 8 s.

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Overlap between angina without obstructive coronary artery disease and left ventricular diastolic dysfunction with preserved ejection fraction

Michelsen, M. M., Pena, A., Mygind, N. D., Høst, N., Gustafsson, I., Hansen, P. R., Hansen, H. S., Kastrup, J. & Prescott, E., 1 maj 2019, I: PLoS One. 14, 5, s. e0216240 e0216240.

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Circulating endostatin as a risk factor for cardiovascular events in patients with stable coronary heart disease: A CLARICOR trial sub-study

Ruge, T., Carlsson, A. C., Kjøller, E., Hilden, J., Kolmos, H. J., Sajadieh, A., Kastrup, J., Jensen, G. B., Larsson, A., Nowak, C., Jakobsen, J. C., Winkel, P., Gluud, C. & Ärnlöv, J., maj 2019, I: Atherosclerosis. 284, s. 202-208 7 s.

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Genetic associations and regulation of expression indicate an independent role for 14q32 snoRNAs in Human Cardiovascular Disease

Håkansson, K. E. J., Goossens, E. A. C., Trompet, S., van Ingen, E., de Vries, M. R., van der Kwast, R. V. C. T., Ripa, R. S., Kastrup, J., Hohensinner, P. J., Kaun, C., Wojta, J., Böhringer, S., le Cessie, S., Jukema, J. W., Quax, P. H. A. & Nossent, A. Y., 1 jan. 2019, I: Cardiovascular Research. 115, 10, s. 1519-1532 14 s.

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Rationale and design of the European multicentre study on Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE)

Paitazoglou, C., Bergmann, M. W., Vrtovec, B., Chamuleau, S. A. J., van Klarenbosch, B., Wojakowski, W., Michalewska-Włudarczyk, A., Gyöngyösi, M., Ekblond, A., Haack-Sørensen, M., Jaquet, K., Vrangbaek, K., Kastrup, J. & SCIENCE Investigators, 1 jan. 2019, I: European Journal of Heart Failure. 21, 8, s. 1032-1041 10 s.

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In Vivo MRI Tracking of Mesenchymal Stromal Cells Labeled with Ultrasmall Paramagnetic Iron Oxide Particles after Intramyocardial Transplantation in Patients with Chronic Ischemic Heart Disease

Mathiasen, A. B., Qayyum, A. A., Jørgensen, E., Helqvist, S., Ekblond, A., Ng, M., Bhakoo, K. & Kastrup, J., 2019, I: Stem Cells International. 2019, s. 2754927

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Cathepsin B and S as markers for cardiovascular risk and all-cause mortality in patients with stable coronary heart disease during 10 years: a CLARICOR trial sub-study

Wuopio, J., Hilden, J., Bring, C., Kastrup, J., Sajadieh, A., Jensen, G. B., Kjøller, E., Kolmos, H. J., Larsson, A., Jakobsen, J. C., Winkel, P., Gluud, C., Carlsson, A. C. & Ärnlöv, J., 1 nov. 2018, I: Atherosclerosis. 278, s. 97-102 6 s.

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Automatic electrocardiographic algorithm for assessing severity of ischemia in ST-segment elevation myocardial infarction

Fakhri, Y., Melgaard, J., Schoos, M. M., Birnbaum, Y., Graff, C., Sejersten, M., Kastrup, J. & Clemmensen, P., 1 okt. 2018, I: International Journal of Cardiology. 268, s. 18-22 5 s.

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Protein biomarkers and coronary microvascular dilatation assessed by rubidium-82 PET in women with angina pectoris and no obstructive coronary artery disease

Schroder, J., Zethner-Moller, R., Bové, K. B., Mygind, N. D., Hasbak, P., Michelsen, M. M., Gustafsson, I., Kastrup, J. & Prescott, E., 1 aug. 2018, I: Atherosclerosis. 275, 8, s. 319-327

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Development of large-scale manufacturing of adipose-derived stromal cells for clinical applications using bioreactors and human platelet lysate

Haack-Sørensen, M., Juhl, M., Follin, B., Harary Søndergaard, R., Kirchhoff, M., Kastrup, J. & Ekblond, A., jul. 2018, I: Scandinavian Journal of Clinical and Laboratory Investigation. 78, 4, s. 293-300 8 s.

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Angiogenesis PET Tracer Uptake (Ga-NODAGA-E[(cRGDyK)]₂) in Induced Myocardial Infarction and Stromal Cell Treatment in Minipigs

Rasmussen, T., Follin, B., Kastrup, J., Brandt-Larsen, M., Madsen, J., Emil Christensen, T., Juhl, M., Cohen, S., Pharao Hammelev, K., Holdflod Møller, C., Peter Goetze, J., Hasbak, P. & Kjær, A., 16 maj 2018, I: Diagnostics. 8, 2, s. E33

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Accelerated collagen turnover in women with angina pectoris without obstructive coronary artery disease: An iPOWER substudy

Nielsen, S. H., Mygind, N. D., Michelsen, M. M., Bechsgaard, D. F., Suhrs, H. E., Genovese, F., Nielsen, H. B., Brix, S., Karsdal, M., Prescott, E. & Kastrup, J., 1 maj 2018, I: European journal of preventive cardiology. 25, 7, s. 719-727

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10-Year Associations Between Tumor Necrosis Factor Receptors 1 and 2 and Cardiovascular Events in Patients With Stable Coronary Heart Disease: A CLARICOR (Effect of Clarithromycin on Mortality and Morbidity in Patients With Ischemic Heart Disease) Trial Substudy

Carlsson, A. C., Ruge, T., Kjøller, E., Hilden, J., Kolmos, H. J., Sajadieh, A., Kastrup, J., Jensen, G. B., Larsson, A., Nowak, C., Jakobsen, J. C., Winkel, P., Gluud, C. & Ärnlöv, J., 23 apr. 2018, I: Journal of the American Heart Association. 7, 9, s. e008299

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Coronary microvascular dysfunction and myocardial contractile reserve in women with angina and no obstructive coronary artery disease

Michelsen, M. M., Pena, A., Mygind, N. D., Bech, J., Gustafsson, I., Kastrup, J., Hansen, H. S., Høst, N., Hansen, P. R. & Prescott, E., feb. 2018, I: Echocardiography (Mount Kisco, N.Y.). 35, 2, s. 196-203

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Ventricular repolarization alterations in women with angina pectoris and suspected coronary microvascular dysfunction

Dose, N., Michelsen, M. M., Mygind, N. D., Pena, A., Ellervik, C., Hansen, P. R., Kanters, J. K., Prescott, E., Kastrup, J., Gustafsson, I., Hansen, H. S. & Steering Committee of the iPOWER study, feb. 2018, I: Journal of Electrocardiology. 51, 1, s. 15-20

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Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: A Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine

Fernández-Avilés, F., Sanz-Ruiz, R., Climent, A. M., Badimon, L., Bolli, R., Charron, D., Fuster, V., Janssens, S., Kastrup, J., Kim, H-S., Lüscher, T. F., Martin, J. F., Menasché, P., Pinto, F. J., Simari, R. D., Stone, G. W., Terzic, A., Willerson, J. T., Wu, J. C. & TACTICS Writing Group, 19 jan. 2018, I: Circulation Research. 122, 2, s. 199-201 3 s.

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Electrocardiographic scores of severity and acuteness of myocardial ischemia predict myocardial salvage in patients with anterior ST-segment elevation myocardial infarction

Fakhri, Y., Sejersten, M., Schoos, M. M., Hansen, H. S., Dubois-Rande, J-L., Hall, T. S., Larsen, A-I., Jensen, S. E., Engblom, H., Arheden, H., Kastrup, J., Atar, D. & Clemmensen, P., 2018, I: Journal of Electrocardiology. 51, 2, s. 195-202

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Prognostic value of routinely available data in patients with stable coronary heart disease. A 10-year follow-up of patients sampled at random times during their disease course

Winkel, P., Jakobsen, J. C., Hilden, J., Jensen, G., Kjøller, E., Sajadieh, A., Kastrup, J., Kolmos, H. J., Larsson, A., Ärnlöv, J. & Gluud, C., 2018, I: Open Heart. 5, 2, s. e000808

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Retention and Functional Effect of Adipose-Derived Stromal Cells Administered in Alginate Hydrogel in a Rat Model of Acute Myocardial Infarction

Follin, B., Ghotbi, A. A., Clemmensen, A. E., Bentsen, S., Juhl, M., Søndergaard, R. H., Lund, L. D., Haack-Sørensen, M., Hasbak, P., Cohen, S., Ripa, R. S., Kastrup, J., Ekblond, A. & Kjær, A., 2018, I: Stem Cells International. 2018, s. 7821461

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YKL-40 in patients with end-stage renal disease receiving haemodialysis

Nielsen, T. L., Plesner, L. L., Warming, P. E., Pallisgaard, J. L., Dalsgaard, M., Schou, M., Høst, U., Rydahl, C., Brandi, L., Køber, L., Johansen, J. S., Kastrup, J. & Iversen, K. K., 2018, I: Biomarkers. 23, 4, s. 357-363 7 s.

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Cryopreserved Off-the-Shelf Allogeneic Adipose-Derived Stromal Cells for Therapy in Patients with Ischemic Heart Disease and Heart Failure-A Safety Study

Kastrup, J., Haack-Sørensen, M., Juhl, M., Harary Søndergaard, R., Follin, B., Drozd Lund, L., Mønsted Johansen, E., Ali Qayyum, A., Bruun Mathiasen, A., Jørgensen, E., Helqvist, S., Jørgen Elberg, J., Bruunsgaard, H. & Ekblond, A., nov. 2017, I: Stem Cells Translational Medicine. 6, 11, s. 1963-1971 9 s.

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Influence of patient related factors on number of mesenchymal stromal cells reached after in vitro culture expansion for clinical treatment

Qayyum, A. A., Kaur, K. P., Mathiasen, A. B., Haack-Sørensen, M., Ekblond, A. & Kastrup, J., nov. 2017, I: Scandinavian Journal of Clinical and Laboratory Investigation. 77, 7, s. 541-548 8 s.

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The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction: rationale and design of the BAMI trial

Mathur, A., Arnold, R., Assmus, B., Bartunek, J., Belmans, A., Bönig, H., Crea, F., Dimmeler, S., Dowlut, S., Fernández-Avilés, F., Galiñanes, M., Garcia-Dorado, D., Hartikainen, J., Hill, J., Hogardt-Noll, A., Homsy, C., Janssens, S., Kala, P., Kastrup, J., Martin, J., Menasche, P., Miklik, R., Mozid, A., San Román, J. A., Sanz-Ruiz, R., Tendera, M., Wojakowski, W., Ylä-Herttuala, S. & Zeiher, A., nov. 2017, I: European Journal of Heart Failure. 19, 11, s. 1545-1550 6 s.

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Global position paper on cardiovascular regenerative medicine

Fernández-Avilés, F., Sanz-Ruiz, R., Climent, A. M., Badimon, L., Bolli, R., Charron, D., Fuster, V., Janssens, S., Kastrup, J., Kim, H-S., Lüscher, T. F., Martin, J. F., Menasché, P., Simari, R. D., Stone, G. W., Terzic, A., Willerson, J. T., Wu, J. C. & TACTICS (Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes) Writing Group, 1 sep. 2017, I: European Heart Journal. 38, 33, s. 2532-2546 15 s.

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Transthoracic Doppler echocardiography compared with positron emission tomography for assessment of coronary microvascular dysfunction: The iPOWER study

Michelsen, M. M., Mygind, N. D., Pena, A., Olsen, R. H., Christensen, T. E., Ghotbi, A. A., Hasbak, P., Kjaer, A., Gustafsson, I., Hansen, P. R., Hansen, H. S., Høst, N., Kastrup, J. & Prescott, E., 1 feb. 2017, I: International Journal of Cardiology. 228, s. 435-443 9 s.

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Algorithm for the automatic computation of the modified Anderson-Wilkins acuteness score of ischemia from the pre-hospital ECG in ST-segment elevation myocardial infarction

Fakhri, Y., Sejersten, M., Schoos, M. M., Melgaard, J., Graff, C., Wagner, G. S., Clemmensen, P. & Kastrup, J., jan. 2017, I: Journal of Electrocardiology. 50, 1, s. 97-101 5 s.

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Senescence and quiescence in adipose-derived stromal cells: Effects of human platelet lysate, fetal bovine serum and hypoxia

Søndergaard, R. H., Follin, B., Lund, L. D., Juhl, M., Ekblond, A., Kastrup, J. & Haack-Sørensen, M., jan. 2017, I: Cytotherapy. 19, 1, s. 95-106 12 s.

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