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Region Hovedstaden - en del af Københavns Universitetshospital
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Clinical translational research on the origins of asthma, atopic dermatitis and allergy. Main contributions:

I.               Inflammation in asthma

II.             Lung function assessment in young children

III.           Asthma therapy and prevention in children

IV.            Genetics in atopic diseases

V.              Microbiome in the early life of asthmatics


Primære forskningsområder

The Copenhagen Prospective Studies on Asthma in Childhood (COPSAC) mother-child cohorts of a total of 1100 children in two main cohorts: COPSAC2000 and COPSAC2010 are being followed closely at the research clinic combining unique extensive clinical data and a comprehensive biobank with cutting-edge interdisciplinary basic research, including genome wide scanning, epigenetics, sequencing of the microbiome in multiple human compartments, and longitudinal metabolomics to develop a differentiated characterization of the disease processes based on a systems biology approach. 

Aktuel forskning

-       The role of the human microbiome in shaping health or disease in the early life

-       Genetics in asthma, allergy and atopic dermatitis

-       The effect of vitamin D supplementation in pregnancy based on a randomized controlled trial (RCT)

-       The effect of fish oil (PUFA) supplementation in pregnancy on the offspring, based on a RCT

-       Low-grade inflammation before the onset of childhood asthma

-       Lung function trajectories from birth to adulthood

-       National registries based studies supporting our findings in the clinic

Mulige interessekonflikter

Consultant at Chiesi Pharmaceuticals and Boeringher-Ingelheim, unrelated to the above

ID: 9997