Personlig profil
Expertise
I am appointed as professor i Gastroenterology and Hepatology with special focus on liver failure. The focus is primarily on patients with acute liver failure and patients with cirrhosis that suddenly decompensate ("acute-on-chronic-liver failure").
Besides these two main areas of focus we also do RCT in patients with autoimmune liver disease, in patients with alcoholic hepatitis, as well as in chronic viral hepatitis.
Primære forskningsområder
Focus is mainly two folded: We study the pathophysiology and try to improvemanagement of the many extrahepatic complications that often develop, such as hepatic encephalopathy, brain edema and cardiovascular dysfunction. The second main focus area is concerned with liver assist devices (high-volume plasmapheresis (HVP), MARS, TetraMARS ect).
Aktuel forskning
HVP improve the survival in patients with acute liver failure. We are now about to launch as similar study in patients with acute-on-chronic-liver failure in cooperation with 6 ICU centers in the US and 16 centers here in Europe. The primary end point will be survival in a RCT design
Mulige interessekonflikter
None
Eksterne ansættelser
Københavns Universitet
2005 → …
Fingeraftryk
- 1 Lignende profiler
Samarbejde og topforskningsområder i de sidste fem år
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Liver support systems and liver transplantation in acute liver failure
Larsen, F. S. & Saliba, F., mar. 2025, I: Liver international : official journal of the International Association for the Study of the Liver. 45, 3, e15633.Publikation: Bidrag til tidsskrift › Review › peer review
15 Citationer (Scopus) -
Therapeutic plasma exchange in amatoxin associated acute liver failure-results from the multi-center Amanita-PEX study
Stahl, K., Nalbant, B., Pape, T., Breteau, I., Coirier, V., Cardoso, F. S., de Haan, J., Janik, M. K., Wasmuth, J.-C., Madaleno, J., Merle, U., Frohme, J., Tepasse, P.-R., Müller, M., Große, K., Linke, A., Mareljic, N., Larsen, F. S., Dahlqvist, G. & Kolev, M. & 31 flere, , 30 okt. 2025, I: Critical care (London, England). 29, 1, 1 s., 458.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
1 Citationer (Scopus) -
Organtransplantation
Perch, M., Bistrup, C., Gustafsson, F., Hornum, M., Jespersen, B., Koefoed-Nielsen, P., Larsen, F. S., Lund, T. K. & Kofod, T., 2024, Medicinsk kompendium. Hauge, E. M., Ainsworth, M. A. & Poulsen, S. D. (red.). 20. udg. Munksgaard , Bind 2.Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Formidling
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Etiology and Outcome of Adult and Pediatric Acute Liver Failure in Europe
Lenz, D., Jørgensen, M. H., Kelly, D., Cardinale, V., Geerts, A., Gonçalves Costa, I., Fichtner, A., Garbade, S. F., Hegen, B., Hilberath, J., de Kleine, R., Kupčinskas, L., McLin, V., Niesert, M., Prado Gonzalez, V., Sturm, E., Staufner, C., Tjwa, E., Willemse, J. & Zecher, B. F. & 3 flere, , 1 jul. 2023, I: Journal of Pediatric Gastroenterology and Nutrition. 77, 1, s. 115-120 6 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
11 Citationer (Scopus) -
Gut Dysbiosis and Blood-Brain Barrier Alteration in Hepatic Encephalopathy: From Gut to Brain
Shahbazi, A., Sepehrinezhad, A., Vahdani, E., Jamali, R., Ghasempour, M., Massoudian, S., Sahab Negah, S. & Larsen, F. S., 25 apr. 2023, I: Biomedicines. 11, 5, 1272.Publikation: Bidrag til tidsskrift › Review › peer review
18 Citationer (Scopus)