Personlig profil
Expertise
Board certified pathologist, Consultant at the Department of Pathology of Rigshospitalet at the University of Copenhagen. Main diagnostic and research area since 2005 has been thoracic pathology and molecular pathology. ESR has published 86 peer-reviewed manuscripts and co-authored 26 book-chapters. He has lectured widely nationally and internationally on thoracic diseases and has staged over 50 oral presentations on pathology and molecular pathology at international meetings.
Primære forskningsområder
Diagnostic and predictive biomarkers for malignant pleura mesothelioma and lung cancer;
Molecular pathology of human cancers;
Thoracic diseases.
Aktuel forskning
Identifying and validating novel diagnostic and predictive biomarkers for malignant pleural mesothelioma and lung cancer using the expression profiles of genes, microRNAs and proteins.
ESR is member of the: International Mesothelioma Interest Group; Advisory Board for Malignant Pleural Mesothelioma of the Danish National Board of Health; Committee for the Danish Cancer Research Foundation; Scientific Board for the Danish Association for Cancer Research; American Association for Cancer Research; European Association for Cancer Research; European Society of Pathology; Thymus & Mediastinum Interest Group; Nordic Thoracic Oncology Group.
Has supervised 8 PhD-students, 4 master students and 4 research assistants. Chairman for 1 PhD defence in Denmark; Opponent for 6 PhD defences in Denmark, Italy, and Norway.
Since 1994, peer reviewer of articles for more than 40 different international journals related to cancer research, pathology and molecular pathology.
Mulige interessekonflikter
During the last 10 years ESR has received honoraria for lectures and expert board-activities from Pfizer, Roche, Novartis, Abbott, and Ely Lilli and one research grant from Pfizer and one from Roche.
Fingeraftryk
- 1 Lignende profiler
Samarbejde og topforskningsområder i de sidste fem år
Publikation
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Bedside Post-Mortem Tissue Biopsy: Diagnostic Approach in ICU Patients?
Toft, B. G., Gjerdrum, L. M. R., Pedersen, U. G., Santoni-Rugiu, E., Willemoe, G. L., Wiese, L., Holm, A. C. & Nielsen, H. B., jan. 2026, I: APMIS - Journal of Pathology, Microbiology and Immunology. 134, 1, s. e70130 e70130.Publikation: Bidrag til tidsskrift › Kommentar/debat › Forskning
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Rygerelaterede interstitielle lungesygdomme
Colnadar, A. D., Mohammad, M., Kjeldgaard, P., Laustrup, L. C., Santoni-Rugiu, E. & Shaker, S. B., 12 jan. 2026, I: Ugeskrift for Laeger. 188, 3, V07250614.Publikation: Bidrag til tidsskrift › Review › peer review
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Targeting uPARAP with an antibody-drug conjugate exhibits efficacy against mesothelioma and synergizes with cisplatin
Çakılkaya, P., Egeland Larsen, I. M., Jiang, Q., Nørregaard, K. S., Gårdsvoll, H., Zhang, J., Jürgensen, H. J., Blomquist, M. H., Perlado, A. M., Krigslund, O., Santoni-Rugiu, E., Engelholm, L. H., Hassan, R. & Behrendt, N., 1 jan. 2026, I: Cancer research communications. 6, 1, s. 130-142 13 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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The recycling collagen receptor uPARAP is a unique mediator of stromal drug delivery to carcinoma cells
Nørregaard, K. S., Larsen, I. M. E., Jürgensen, H. J., Blomquist, M. H., Çakılkaya, P., Metrangolo, V., Perlado, A. M., Krigslund, O., Gårdsvoll, H., Poulsen, T. T., Mumberg, D., Santoni-Rugiu, E., Engelholm, L. H. & Behrendt, N., 2 jan. 2026, I: Molecular Cancer Therapeutics. 25, 1, s. 140-155 16 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Advances in diagnosis and management of pleural mesothelioma: the Danish clinical guidelines
Panou, V., Sørensen, J. B., Ravn, J. & Santoni-Rugiu, E., 2025, I: European Clinical Respiratory Journal. 12, 1, s. 2580795 2580795.Publikation: Bidrag til tidsskrift › Review › peer review