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Region Hovedstaden - en del af Københavns Universitetshospital
Cristina  Legido-Quigley

Cristina Legido-Quigley

Forskningsleder

Niels Steensens Vej 2-4

2820 Gentofte

Danmark

  1. 2018
  2. Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study

    Varma, V. R., Oommen, A. M., Varma, S., Casanova, R., An, Y., Andrews, R. M., O’Brien, R., Pletnikova, O., Troncoso, J. C., Toledo, J., Baillie, R., Arnold, M., Kastenmueller, G., Nho, K., Doraiswamy, P. M., Saykin, A. J., Kaddurah-Daouk, R., Legido-Quigley, C. & Thambisetty, M., 1 jan. 2018, I: PLOS Medicine. 15, 1, e1002482.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  3. Udgivet

    Combined transcriptomics and metabolomics analyses of adipose tissue in obese subjects reveal pathways associated with insulin resistance

    Al-Sari, N. H., Dahlman, I., Kolehmainen, M., Legido-Quigley, C., Ahonen, L. L., Dragsted, L. O. & Ali, A., 2018.

    Publikation: KonferencebidragKonferenceabstrakt til konferenceForskning

  4. Determination of glucosamine in food supplements by HILIC-ESI-MS

    Zheng, L., Han, P., Kim, M. & Legido-Quigley, C., 2018, I: European Pharmaceutical Review.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskning

  5. Evidence for brain glucose dysregulation in Alzheimer's disease

    An, Y., Varma, V. R., Varma, S., Casanova, R., Dammer, E., Pletnikova, O., Chia, C. W., Egan, J. M., Ferrucci, L., Troncoso, J., Levey, A. I., Lah, J., Seyfried, N. T., Legido-Quigley, C., O'Brien, R. & Thambisetty, M., 2018, I: Alzheimer's & dementia : the journal of the Alzheimer's Association.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  6. Udgivet
  7. 2017
  8. Metabolic network failures in Alzheimer's disease: A biochemical road map

    Toledo, J. B., Arnold, M., Kastenmüller, G., Chang, R., Baillie, R. A., Han, X., Thambisetty, M., Tenenbaum, J. D., Suhre, K., Thompson, J. W., John-Williams, L. S., MahmoudianDehkordi, S., Rotroff, D. M., Jack, J. R., Motsinger-Reif, A., Risacher, S. L., Blach, C., Lucas, J. E., Massaro, T., Louie, G., Zhu, H., Dallmann, G., Klavins, K., Koal, T., Kim, S., Nho, K., Shen, L., Casanova, R., Varma, S., Legido-Quigley, C., Moseley, M. A., Zhu, K., Henrion, M. Y. R., van der Lee, S. J., Harms, A. C., Demirkan, A., Hankemeier, T., van Duijn, C. M., Trojanowski, J. Q., Shaw, L. M., Saykin, A. J., Weiner, M. W., Doraiswamy, P. M., Kaddurah-Daouk, R. & Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium, sep. 2017, I: Alzheimer's & dementia : the journal of the Alzheimer's Association. 13, 9, s. 965-984 20 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  9. Direct Monitoring of Exogenous γ-Hydroxybutyric Acid in Body Fluids by NMR Spectroscopy

    Palomino-Schätzlein, M., Wang, Y., Brailsford, A. D., Parella, T., Cowan, D. A., Legido-Quigley, C. & Pérez-Trujillo, M., 15 aug. 2017, I: Analytical Chemistry. 89, 16, s. 8343-8350 8 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  10. Transient receptor potential canonical 5 channels plays an essential role in hepatic dyslipidemia associated with cholestasis

    Alawi, K. M., Tandio, D., Xu, J., Thakore, P., Papacleovoulou, G., Fernandes, E. S., Legido-Quigley, C., Williamson, C. & Brain, S. D., 24 maj 2017, I: Scientific Reports. 7, 1, s. 2338

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  11. Peril beyond the winner's curse: A small sample size is the bane of biomarker discovery

    Thambisetty, M., Casanova, R., Varma, S. & Legido Quigley, C., maj 2017, I: Alzheimer's & dementia : the journal of the Alzheimer's Association. 13, 5, s. 606-607 2 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  12. Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study

    Snowden, S. G., Ebshiana, A. A., Hye, A., An, Y., Pletnikova, O., O'Brien, R., Troncoso, J., Legido-Quigley, C. & Thambisetty, M., mar. 2017, I: PLOS Medicine. 14, 3, s. e1002266

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  13. Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis

    Proitsi, P., Kim, M., Whiley, L., Simmons, A., Sattlecker, M., Velayudhan, L., Lupton, M. K., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C., feb. 2017, I: Alzheimer's & dementia : the journal of the Alzheimer's Association. 13, 2, s. 140-151 12 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  14. Alpha-synuclein in Bio Fluids and Tissues as a Potential Biomarker for Parkinson’s Disease

    Shah, A., Hiew, K. W., Han, P., Parsons, R., Chang, R. C-C. & Legido-Quigley, C., 2017, I: Journal of Alzheimer's Parkinsonism & Dementia.

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  15. Association between Plasma Ceramides and Phosphatidylcholines and Hippocampal Brain Volume in Late Onset Alzheimer's Disease

    Kim, M., Nevado-Holgado, A., Whiley, L., Snowden, S. G., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Thambisetty, M., Dobson, R. J. B., Powell, J. F., Lupton, M. K., Simmons, A., Velayudhan, L., Lovestone, S., Proitsi, P. & Legido-Quigley, C., 2017, I: Journal of Alzheimer's disease : JAD. 60, 3, s. 809-817 9 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  16. Metabolic phenotyping in the mouse model of urinary tract infection shows that 3-hydroxybutyrate in plasma is associated with infection

    Han, P., Huang, Y., Xie, Y., Yang, W., Wang, Y., Xiang, W., Hylands, P. J. & Legido-Quigley, C., 2017, I: P L o S One. 12, 10, s. e0186497

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  17. 2016
  18. Blood metabolite markers of cognitive performance and brain function in aging

    Simpson, B. N., Kim, M., Chuang, Y. F., Beason-Held, L., Kitner-Triolo, M., Kraut, M., Lirette, S. T., Windham, B. G., Griswold, M. E., Legido-Quigley, C. & Thambisetty, M., 1 jul. 2016, I: Journal of Cerebral Blood Flow and Metabolism. 36, 7, s. 1212-1223 12 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  19. Blood metabolite markers of preclinical Alzheimer's disease in two longitudinally followed cohorts of older individuals

    Casanova, R., Varma, S., Simpson, B., Kim, M., An, Y., Saldana, S., Riveros, C., Moscato, P., Griswold, M., Sonntag, D., Wahrheit, J., Klavins, K., Jonsson, P. V., Eiriksdottir, G., Aspelund, T., Launer, L. J., Gudnason, V., Legido Quigley, C. & Thambisetty, M., 1 jul. 2016, I: Alzheimer's and Dementia. 12, 7, s. 815-822 8 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  20. Assessment of Polygonum capitatum Buch.-Ham. ex D.Don by metabolomics based on gas chromatography with mass spectrometry

    Han, P., Huang, Y., Hylands, P. J. & Legido-Quigley, C., 1 maj 2016, I: Journal of Separation Science. 39, 10, s. 1979-1986 8 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  21. LC-MS-Based Metabolomics Discovers Purine Endogenous Associations with Low-Dose Salbutamol in Urine Collected for Antidoping Tests

    Wang, Y., Caldwell, R., Cowan, D. A. & Legido-Quigley, C., 16 feb. 2016, I: Analytical Chemistry. 88, 4, s. 2243-2249 7 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  22. The impact of ischemia/reperfusion injury on liver allografts from deceased after cardiac death versus deceased after brain death donors

    Xu, J., Sayed, B. A., Casas-Ferreira, A. M., Srinivasan, P., Heaton, N., Rela, M., Ma, Y., Fuggle, S., Legido-Quigley, C. & Jassem, W., 1 feb. 2016, I: PLoS One. 11, 2, e0148815.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  23. Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins

    Alzheimer's Disease Neuroimaging Initiative, 26 jan. 2016, I: Translational psychiatry. 6, s. e719

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  24. 2015
  25. Lipidomics comparing DCD and DBD liver allografts uncovers lysophospholipids elevated in recipients undergoing early allograft dysfunction

    Xu, J., Casas-Ferreira, A. M., Ma, Y., Sen, A., Kim, M., Proitsi, P., Shkodra, M., Tena, M., Srinivasan, P., Heaton, N., Jassem, W. & Legido-Quigley, C., 4 dec. 2015, I: Scientific Reports. 5, s. 17737

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  26. Adenosine monophosphate is elevated in the bronchoalveolar lavage fluid of mice with acute respiratory toxicity induced by nanoparticles with high surface hydrophobicity

    Dailey, L. A., Hernández-Prieto, R., Casas-Ferreira, A. M., Jones, M-C., Riffo-Vasquez, Y., Rodríguez-Gonzalo, E., Spina, D., Jones, S. A., Smith, N. W., Forbes, B., Page, C. & Legido-Quigley, C., feb. 2015, I: Nanotoxicology. 9, 1, s. 106-15 10 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  27. Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer's disease

    Proitsi, P., Kim, M., Whiley, L., Pritchard, M., Leung, R., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Sham, P., Lovestone, S., Powell, J. F., Dobson, R. J. B. & Legido-Quigley, C., 13 jan. 2015, I: Translational psychiatry. 5, s. e494

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  28. Metabolomic method: UPLC-q-ToF polar and non-polar metabolites in the healthy rat cerebellum using an in-vial dual extraction

    Ebshiana, A. A., Snowden, S. G., Thambisetty, M., Parsons, R., Hye, A. & Legido-Quigley, C., 2015, I: PLoS One. 10, 4, s. e0122883

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  29. 2014
  30. Investigating sub-2 μm particle stationary phase supercritical fluid chromatography coupled to mass spectrometry for chemical profiling of chamomile extracts

    Jones, M. D., Avula, B., Wang, Y-H., Lu, L., Zhao, J., Avonto, C., Isaac, G., Meeker, L., Yu, K., Legido-Quigley, C., Smith, N. & Khan, I. A., 17 okt. 2014, I: Analytica Chimica Acta. 847, s. 61-72 12 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  31. Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease

    AddNeuroMed Consortium, feb. 2014, I: Neurobiology of Aging. 35, 2, s. 271-8 8 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  32. Multidimensional LC-MS/MS enables simultaneous quantification of intact human insulin and five recombinant analogs in human plasma

    Chambers, E. E., Fountain, K. J., Smith, N., Ashraf, L., Karalliedde, J., Cowan, D. & Legido-Quigley, C., 7 jan. 2014, I: Analytical Chemistry. 86, 1, s. 694-702 9 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  33. 2013
  34. High sensitivity LC-MS/MS method for direct quantification of human parathyroid 1-34 (teriparatide) in human plasma

    Chambers, E. E., Lame, M. E., Bardsley, J., Hannam, S., Legido-Quigley, C., Smith, N., Fountain, K. J., Collins, E. & Thomas, E., 1 nov. 2013, I: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 938, s. 96-104 9 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  35. In-vial dual extraction liquid chromatography coupled to mass spectrometry applied to streptozotocin-treated diabetic rats. Tips and pitfalls of the method

    Godzien, J., Ciborowski, M., Whiley, L., Ruperez, F. J., Barbas, C. & Legido-Quigley, C., 23 aug. 2013, I: Journal of Chromatography. 1304, s. 52-60 9 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  36. Metabolic phenotype of the healthy rodent model using in-vial extraction of dried serum, urine, and cerebrospinal fluid spots

    Sen, A., Wang, Y., Chiu, K., Whiley, L., Cowan, D., Chang, R. C-C. & Legido-Quigley, C., 6 aug. 2013, I: Analytical Chemistry. 85, 15, s. 7257-63 7 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  37. Development of a fast method for direct analysis of intact synthetic insulins in human plasma: the large peptide challenge

    Chambers, E. E., Legido-Quigley, C., Smith, N. & Fountain, K. J., jan. 2013, I: Bioanalysis. 5, 1, s. 65-81 17 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  38. Capillary and Micro High Performance Liquid Chromatography

    Smith, N., Legido-Quigley, C., Marlin, N., Melin, V. & Mutton, I., 2013, Capillary and Micro High Performance Liquid Chromatography. Elsevier

    Publikation: Bidrag til bog/antologi/rapportBidrag til bog/antologiForskningpeer review

  39. 2012
  40. In-vial dual extraction for direct LC-MS analysis of plasma for comprehensive and highly reproducible metabolic fingerprinting

    Whiley, L., Godzien, J., Ruperez, F. J., Legido-Quigley, C. & Barbas, C., 17 jul. 2012, I: Analytical Chemistry. 84, 14, s. 5992-9 8 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  41. Comparison of reversed-phase and hydrophilic interaction liquid chromatography for the separation of ephedrines

    Heaton, J., Gray, N., Cowan, D. A., Plumb, R. S., Legido-Quigley, C. & Smith, N. W., 9 mar. 2012, I: Journal of Chromatography. 1228, s. 329-37 9 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  42. UV gradient combined with principal component analysis: highly sensitive and specific high performance liquid chromatography analysis of cosmetic creams

    Gao, W., Gray, N., Heaton, J., Smith, N. W., Jia, Y. & Legido-Quigley, C., 9 mar. 2012, I: Journal of Chromatography. 1228, s. 324-8 5 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  43. 2011
  44. Systematic evaluation of acetone and acetonitrile for use in hydrophilic interaction liquid chromatography coupled with electrospray ionization mass spectrometry of basic small molecules

    Heaton, J., Jones, M. D., Legido-Quigley, C., Plumb, R. S. & Smith, N. W., 30 dec. 2011, I: Rapid Communications in Mass Spectrometry. 25, 24, s. 3666-74 9 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  45. Bile UPLC-MS fingerprinting and bile acid fluxes during human liver transplantation

    Legido-Quigley, C., McDermott, L., Vilca-Melendez, H., Murphy, G. M., Heaton, N., Lindon, J. C., Nicholson, J. K. & Holmes, E., aug. 2011, I: Electrophoresis. 32, 15, s. 2063-70 8 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  46. Fast and sensitive high performance liquid chromatography analysis of cosmetic creams for hydroquinone, phenol and six preservatives

    Gao, W. & Legido-Quigley, C., 15 jul. 2011, I: Journal of Chromatography. 1218, 28, s. 4307-11 5 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  47. Rapid quantification of quinine and its major metabolite (3S)-3-hydroxyquinine in diluted urine by UPLC-MS/MS

    Heaton, J., Rahmioglu, N., Ahmadi, K. R., Legido-Quigley, C. & Smith, N. W., 1 jun. 2011, I: Journal of Pharmaceutical and Biomedical Analysis. 55, 3, s. 494-9 6 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  48. Current strategies in the discovery of small-molecule biomarkers for Alzheimer's disease

    Whiley, L. & Legido-Quigley, C., maj 2011, I: Bioanalysis. 3, 10, s. 1121-42 22 s.

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  49. Evaluation of Chinese medicinal herbs fingerprinting by HPLC-DAD for the detection of toxic aristolochic acids

    Heaton, J., Whiley, L., Hong, Y., Sebastian, C. M., Smith, N. W. & Legido-Quigley, C., maj 2011, I: Journal of Separation Science. 34, 10, s. 1111-5 5 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  50. 2010
  51. Metabolite-biomarker investigations in the life cycle of and infection with Schistosoma

    Legido-Quigley, C., aug. 2010, I: Parasitology. 137, 9, s. 1425-35 11 s.

    Publikation: Bidrag til tidsskriftReviewForskningpeer review

  52. Chemometric analysis of urine fingerprints acquired by liquid chromatography-mass spectrometry and capillary electrophoresis: application to the schistosomiasis mouse model

    Garcia-Perez, I., Earll, M. E., Angulo, S., Barbas, C. & Legido-Quigley, C., jul. 2010, I: Electrophoresis. 31, 14, s. 2349-55 7 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  53. Chemometric and biological validation of a capillary electrophoresis metabolomic experiment of Schistosoma mansoni infection in mice

    Garcia-Perez, I., Angulo, S., Utzinger, J., Holmes, E., Legido-Quigley, C. & Barbas, C., jul. 2010, I: Electrophoresis. 31, 14, s. 2338-48 11 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  54. Guidelines for reporting the use of capillary electrophoresis in proteomics

    Minimum Information About a Proteomics Experiment (MIAPE), jul. 2010, I: Nature Biotechnology. 28, 7, s. 654-5 2 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  55. Guidelines for reporting the use of column chromatography in proteomics

    Minimum Information About a Proteomics Experiment (MIAPE), jul. 2010, I: Nature Biotechnology. 28, 7, s. 654

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  56. Liquid chromatography-mass spectrometry methods for urinary biomarker detection in metabonomic studies with application to nutritional studies

    Legido-Quigley, C., Stella, C., Perez-Jimenez, F., Lopez-Miranda, J., Ordovas, J., Powell, J., van-der-Ouderaa, F., Ware, L., Lindon, J. C., Nicholson, J. K. & Holmes, E., jul. 2010, I: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 24, 7, s. 737-43 7 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  57. Bidirectional correlation of NMR and capillary electrophoresis fingerprints: a new approach to investigating Schistosoma mansoni infection in a mouse model

    Garcia-Perez, I., Couto Alves, A., Angulo, S., Li, J. V., Utzinger, J., Ebbels, T. M. D., Legido-Quigley, C., Nicholson, J. K., Holmes, E. & Barbas, C., 1 jan. 2010, I: Analytical Chemistry. 82, 1, s. 203-10 8 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

  58. Are Separation Scientists suited to Metabolomics?

    Legido-Quigley, C. & smith, N., 2010

    Publikation: Bog/antologi/afhandling/rapportRapportpeer review

  59. 2009
  60. First example of hepatocyte transplantation to alleviate ornithine transcarbamylase deficiency, monitored by NMR-based metabonomics

    Legido-Quigley, C., Cloarec, O., Parker, D. A., Murphy, G. M., Holmes, E., Lindon, J. C., Nicholson, J. K., Mitry, R. R., Vilca-Melendez, H., Rela, M., Dhawan, A. & Heaton, N., dec. 2009, I: Bioanalysis. 1, 9, s. 1527-35 9 s.

    Publikation: Bidrag til tidsskriftTidsskriftartikelForskningpeer review

ID: 52380068