Publikationer pr. år
Publikationer pr. år
Personlig profil
Expertise
Specialist in Respiratory Medicine; Clinical researcher; translational scientist.
Obstructive airways disease; asthma; COPD; inflammation; pathophysiology
Primære forskningsområder
My research interests revolve around the diagnosis and phenotyping of asthma, with a focus on airway pathophysiology and inflammation. Hence, my Ph.D. thesis from 2006 described the usefulness of bronchial provocation testing with mannitol for assessing inflammation driven airway hyperresponsiveness. The mannitol test is now widely used as a diagnostic test for asthma in the clinical setting.
During my post doc with Prof Peter Gibsons group and Prof Greg King in Australia in 2010-11, I described the relationships between airway pathophysiology and subtypes of airway inflammation in older adults with asthma. These findings have added to our understanding of older asthma patients; an overlooked and often undertreated group of asthma patients.
Aktuel forskning
Current research projects include studies on severe asthma: Prevalence, disease mechanisms, phenotypes immunology, novel treatments. Furthermore COPD: Immunological phenotypes and prognosis
A key aim of my research is to address key clinical problems in translational research studies, in order to provide better solutions to the management of the most severely ill patients with obstructive airways disease.
Mulige interessekonflikter
Unrestricted research grants, honoraria for scientific presentations, consultancies from pharmaceutical companies:
Novartis
Teva
Nigaard
Takeda
Pharmaxis
Norpharma
Boehringer
Astra Zeneca
Jannsen
GSK
Sandoz
Roche
Icepharma
Fingeraftryk
Dyk ned i forskningsemnerne, hvor Celeste Porsbjerg er aktive. Disse emneetiketter kommer fra denne persons arbejder. Sammen danner de et unikt fingerprint.
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Netværk
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Airway hyperresponsiveness reflects corticosteroid-sensitive mast cell involvement across asthma phenotypes
Hvidtfeldt, M., Sverrild, A., Pulga, A., Frøssing, L., Silberbrandt, A., Hostrup, M., Thomassen, M., Sanden, C., Clausson, C. M., Siddhuraj, P., Bornesund, D., Nieto-Fontarigo, J. J., Uller, L., Erjefält, J. & Porsbjerg, C., 10 mar. 2023, I: The Journal of allergy and clinical immunology.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Allergen Immunotherapy Enhances Airway Epithelial Antiviral Immunity in Patients with Allergic Asthma (VITAL Study): A Double Blind Randomized Controlled Trial
Woehlk, C., Ramu, S., Sverrild, A., Nieto-Fontarigo, J. J., Vázquez-Mera, S., Cerps, S., Pulga, A., Andreasson, L. M., Eriksen, L. L., Dyhre-Petersen, N., Menzel, M., Klein, D. K., Hansen, S., Uller, L. & Porsbjerg, C., 1 maj 2023, I: American Journal of Respiratory and Critical Care Medicine. 207, 9, s. 1161-1170 10 s.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Asthma
Porsbjerg, C., Melén, E., Lehtimäki, L. & Shaw, D., 11 mar. 2023, I: Lancet. 401, 10379, s. 858-873 16 s.Publikation: Bidrag til tidsskrift › Review › peer review
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Asthma: Closing in on the Biology of a Complex Life-Course Disease
Bush, A., Holguin, F., Porsbjerg, C. & Saglani, S., 4 jan. 2023, (E-pub ahead of print) I: American Journal of Respiratory and Critical Care Medicine.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review
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Comparative effectiveness of Anti-IL5 and Anti-IgE biologic classes in patients with severe asthma eligible for both
Pfeffer, P. E., Ali, N., Murray, R., Ulrik, C., Tran, T. N., Maspero, J., Peters, M., Christoff, G. C., Sadatsafavi, M., Torres-Duque, C. A., Altraja, A., Lehtimäki, L., Papadopoulos, N. G., Salvi, S., Costello, R. W., Cushen, B., Heffler, E., Iwanaga, T., Al-Ahmad, M., Larenas-Linnemann, D., & 49 flere, 17 mar. 2023, (E-pub ahead of print) I: Allergy.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review