Bodil Elise Thorhauge Als-Nielsen

Publikation

Publikationer pr. år 2002 2010 2020 2021 2022 2023

• 26 Tidsskriftartikel
• 3 Review
• 1 Ph.d.-afhandling

Publikationer pr. år

Publikationer pr. år

Søgeresultater

• 2023

  Physician-defined severe toxicities occurring during and after cancer treatment: Modified consensus definitions and clinical applicability in the evaluation of cancer treatment

  Nielsen, C. G., Thomsen, B. L., Als-Nielsen, B., Conyers, R., Jeha, S., Mateos, M. K., Mlynarski, W., Pieters, R., Rathe, M., Schmiegelow, K. & Andrés-Jensen, L., 2023, I: Frontiers in Pediatrics. 11, s. 1155449 1155449.

  Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › peer review

  • Physicians 100%
  • Neoplasms 51%
  • Cancer Survivors 43%
  • Young Adult 32%
  • Therapeutics 25%
• 2022

  Acute central nervous system toxicity during treatment of pediatric acute lymphoblastic leukemia: phenotypes, risk factors and genotypes

  Anastasopoulou, S., Nielsen, R. L., Als-Nielsen, B., Banerjee, J., Eriksson, M. A., Helenius, M., Heyman, M. M., Johannsdottir, I. M., Jonsson, O. G., MacGregor, S., Mateos, M. K., Mayoh, C., Mikkel, S., Myrberg, I. H., Niinimäki, R., Schmiegelow, K., Taskinen, M., Vaitkeviciene, G., Warnqvist, A., Wolthers, B., & 2 flereHarila-Saari, A. & Ranta, S., 1 okt. 2022, I: Haematologica. 107, 10, s. 2318-2328 11 s.

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  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Central Nervous System 75%
  • Genotype 72%
  • Pediatrics 65%
  • Phenotype 61%

• DNA-thioguanine concentration and relapse risk in children and young adults with acute lymphoblastic leukemia: an IPD meta-analysis

  Toksvang, L. N., Grell, K., Nersting, J., Degn, M., Nielsen, S. N., Abrahamsson, J., Lund, B., Kanerva, J., Jónsson, Ó. G., Lepik, K., Vaitkevičienė, G., Griškevičius, L., Quist-Paulsen, P., Vora, A., Moorman, A. V., Murdy, D., Zimmermann, M., Möricke, A., Bostrom, B., Joshi, J., & 4 flereHjalgrim, L. L., Dalhoff, K. P., Als-Nielsen, B. & Schmiegelow, K., jan. 2022, I: Leukemia. 36, 1, s. 33-41 9 s.

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  • Thioguanine 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 70%
  • Young Adult 58%
  • Meta-Analysis 53%
  • Recurrence 41%

• Does minimal central nervous system involvement in childhood acute lymphoblastic leukemia increase the risk for central nervous system toxicity?

  Anastasopoulou, S., Harila-Saari, A., Als-Nielsen, B., Eriksson, M. A., Heyman, M., Johannsdottir, I. M., Marquart, H. V., Niinimäki, R., Pronk, C. J., Schmiegelow, K., Vaitkeviciene, G., Thastrup, M. & Ranta, S., jul. 2022, I: Pediatric Blood & Cancer. 69, 7, s. 1-5 5 s., e29745.

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  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Central Nervous System 75%
  • Posterior Leukoencephalopathy Syndrome 49%
  • Seizures 26%
  • Confidence Intervals 13%
  1 Citationer (Scopus)

• Socioeconomic position and maintenance therapy in children with acute lymphoblastic leukemia: A national cohort study

  Pedersen, L. H., Østergaard, A., Bank, V., Nersting, J., Tuckuviene, R., Wehner, P. S., Albertsen, B. K., Degn, M., Als-Nielsen, B. E. T., Larsen, H. B., Schmiegelow, K. & Dalton, S. O., jul. 2022, I: Pediatric Blood & Cancer. 69, 7, s. 1-10 10 s., e29508.

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  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Cohort Studies 69%
  • Mercaptopurine 67%
  • Methotrexate 49%
  • Child 44%
  2 Citationer (Scopus)

• Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol

  Toksvang, L. N., Als-Nielsen, B., Bacon, C., Bertasiute, R., Duarte, X., Escherich, G., Helgadottir, E. A., Johannsdottir, I. R., Jónsson, Ó. G., Kozlowski, P., Langenskjöld, C., Lepik, K., Niinimäki, R., Overgaard, U. M., Punab, M., Räty, R., Segers, H., van der Sluis, I., Smith, O. P., Strullu, M., & 4 flereVaitkevičienė, G., Wik, H. S., Heyman, M. & Schmiegelow, K., 2 maj 2022, I: BMC Cancer. 22, 1, s. 1-19 19 s., 483.

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  • T-Lymphoid Precursor Cells 100%
  • Thioguanine 97%
  • Mercaptopurine 93%
  • B-Lymphoid Precursor Cells 84%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 68%
• 2021

  Aspergillus flavus Infections in Children With Leukemia Despite Liposomal Amphotericin-B Prophylaxis

  Vissing, N. H., Lausen, B., Hutchings Hoffmann, M., Als-Nielsen, B., Schmiegelow, K., Helweg-Larsen, J., Arendrup, M. C. & Nygaard, U., 1 aug. 2021, I: The Pediatric infectious disease journal. 40, 8, s. 749-752 4 s.

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  • Aspergillus flavus 100%
  • liposomal amphotericin B 94%
  • Aspergillosis 82%
  • Leukemia 56%
  • Child 30%
  2 Citationer (Scopus)

• Dynamics of leucocyte DNA thioguanine nucleotide levels during maintenance therapy of childhood acute lymphoblastic leukemia

  Larsen, R. H., Hjalgrim, L. L., Degn, M., Nersting, J., Als-Nielsen, B., Grell, K. & Schmiegelow, K., jul. 2021, I: Cancer Chemotherapy and Pharmacology. 88, 1, s. 53-60 8 s.

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  • Thioguanine 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 70%
  • Nucleotide 58%
  • Nucleotides 57%
  • Leukocytes 56%

• Increments in DNA-thioguanine level during thiopurine enhanced maintenance therapy of acute lymphoblastic leukemia

  Larsen, R. H., Utke Rank, C., Grell, K., Nørgaard Møller, L., Malthe Overgaard, U., Kampmann, P., Nersting, J., Degn, M., Nygaard Nielsen, S., Holst, H., Klug Albertsen, B., Skov Wehner, P., Thude Callesen, M., Kanerva, J., Leth Frandsen, T., Als-Nielsen, B., Lyngsie Hjalgrim, L. & Schmiegelow, K., 1 nov. 2021, I: Haematologica. 106, 11, s. 2824-2833 10 s.

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  • Thioguanine 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 70%
  • DNA 40%
  • Methotrexate 26%
  • purine 25%

• Quantification of Methotrexate in Human Serum Using Surface-Enhanced Raman Scattering-Toward Therapeutic Drug Monitoring

  Göksel, Y., Zor, K., Rindzevicius, T., Thorhauge Als-Nielsen, B. E., Schmiegelow, K. & Boisen, A., 23 jul. 2021, I: ACS sensors. 6, 7, s. 2664-2673 10 s.

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  • Raman scattering 100%
  • Methotrexate 86%
  • serums 82%
  • drugs 69%
  • Nanopillars 59%
• 2020

  Pharmacokinetics of tablet and liquid formulations of oral 6-mercaptopurine in children with acute lymphoblastic leukemia

  Larsen, R. H., Hjalgrim, L. L., Grell, K., Kristensen, K., Pedersen, L. G., Brünner, E. D., Als-Nielsen, B., Schmiegelow, K. & Nersting, J., jul. 2020, I: Cancer Chemotherapy and Pharmacology. 86, 1, s. 25-32 8 s.

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  • Mercaptopurine 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 73%
  • Tablets 68%
  • Pharmacokinetics 56%
  • Liquid 40%

• Seizures during treatment of childhood acute lymphoblastic leukemia: A population-based cohort study

  Anastasopoulou, S., Heyman, M., Eriksson, M. A., Niinimäki, R., Taskinen, M., Mikkel, S., Vaitkeviciene, G. E., Johannsdottir, I. M., Myrberg, I. H., Jonsson, O. G., Als-Nielsen, B., Schmiegelow, K., Banerjee, J., Ranta, S. & Harila-Saari, A., jul. 2020, I: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. 27, s. 72-77 6 s.

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  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Seizures 78%
  • Cohort Studies 69%
  • Population 39%
  • Posterior Leukoencephalopathy Syndrome 29%
• 2019

  Posterior reversible encephalopathy syndrome in children with acute lymphoblastic leukemia: Clinical characteristics, risk factors, course, and outcome of disease

  Anastasopoulou, S., Eriksson, M. A., Heyman, M., Wang, C., Niinimäki, R., Mikkel, S., Vaitkevičienė, G. E., Johannsdottir, I. M., Myrberg, I. H., Jonsson, O. G., Als-Nielsen, B., Schmiegelow, K., Banerjee, J., Harila-Saari, A. & Ranta, S., 2019, I: Pediatric Blood & Cancer. 66, 5, s. e27594 e27594.

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  • Posterior Leukoencephalopathy Syndrome 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 67%
  • Child 29%
  • Hematology 13%
  • Central Nervous System 9%
  29 Citationer (Scopus)
• 2017

  Cerebral near-infrared spectroscopy monitoring for prevention of brain injury in very preterm infants

  Hyttel-Sorensen, S., Greisen, G., Als-Nielsen, B. & Gluud, C., 4 sep. 2017, I: Cochrane Database of Systematic Reviews. 9, s. CD011506

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  • Near-Infrared Spectroscopy 100%
  • Brain Injuries 81%
  • Premature Infants 80%
  • Randomized Controlled Trials 19%
  • Guidelines 19%
  6 Citationer (Scopus)
• 2015

  Cerebral near-infrared spectroscopy monitoring for prevention of brain injury in very preterm infants (Protocol)

  Hyttel-Sørensen, S., Støy, L., Greisen, G., Als-Nielsen, B. E. T. & Gluud, C., 2015, I: Cochrane Database of Systematic Reviews. 2, s. CD011506

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• 2014

  Dopamine agents for hepatic encephalopathy

  Junker, A. E., Als-Nielsen, B., Gluud, C. & Gluud, L. L., 10 feb. 2014, I: Cochrane Database of Systematic Reviews. 2, s. CD003047

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  • Dopamine Agents 100%
  • Hepatic Encephalopathy 94%
  • Parkinson Disease 33%
  • Bromocriptine 24%
  • Levodopa 22%
  10 Citationer (Scopus)
• 2012

  Influence of reported study design characteristics on intervention effect estimates from randomised controlled trials: combined analysis of meta-epidemiological studies

  Savović, J., Jones, H., Altman, D., Harris, R., Jűni, P., Pildal, J., Als-Nielsen, B., Balk, E., Gluud, C., Gluud, L. L., Ioannidis, J., Schulz, K., Beynon, R., Welton, N., Wood, L., Moher, D., Deeks, J. & Sterne, J., 2012, I: Health Technology Assessment. 16, 35, s. 1-82 82 s.

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  • epidemiological studies 100%
  • Epidemiologic Studies 70%
  • Occupational Groups 60%
  • Randomized Controlled Trials 57%
  • Control Groups 45%
  516 Citationer (Scopus)

• Influence of reported study design characteristics on intervention effect estimates from randomized, controlled trials

  Savović, J., Jones, H. E., Altman, D. G., Harris, R. J., Jüni, P., Pildal, J., Als-Nielsen, B. E. T., Balk, E. M., Gluud, C., Gluud, L. L., Ioannidis, J. P. A., Schulz, K. F., Beynon, R., Welton, N. J., Wood, L., Moher, D., Deeks, J. J. & Sterne, J. A. C., 2012, I: Annals of Internal Medicine. 157, 6, s. 429-38 10 s.

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  • Randomized Controlled Trials 100%
  • Odds Ratio 95%
  • Mortality 49%
  • Epidemiologic Studies 41%
  • Datasets 39%
  806 Citationer (Scopus)
• 2011

  Development of a combined database for meta-epidemiological research

  Savović, J., Harris, R. J., Wood, L., Beynon, R., Altman, D., Als-Nielsen, B., Balk, E. M., Deeks, J., Gluud, L. L., Gluud, C., Loannidis, J. P. A., Jűni, P., Moher, D., Pildal, J., Schulz, K. F. & Sterne, J. A. C., mar. 2011, I: Research Synthesis Methods. 2, 1, s. 78

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• Hepato-biliary clinical trials and their inclusion in the Cochrane Hepato-Biliary Group register and reviews

  Klingenberg, S. L., Nikolova, D., Alexakis, N., Als-Nielsen, B., Colli, A., Conte, D., D'Amico, G., Davidson, B., Fingerhut, A., Fraquelli, M., Gluud, L. L., Gurusamy, K., Keus, F., Khan, S., Koretz, R., van Laarhoven, C., Liu, J., Myers, R., Pagliaro, L., Simonetti, R., & 3 flereSutton, R., Thorlund, K. & Gluud, C., 2011, I: Journal of Gastroenterology and Hepatology. 26, 4, s. 649-56 8 s.

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  • Systematic Reviews 100%
  • Clinical Trials 88%
  • Controlled Clinical Trials 73%
  • Focus Groups 65%
  • Meta-Analysis 50%
  3 Citationer (Scopus)
• 2010

  Chlamydia pneumoniae IgG and IgA antibody titers and prognosis in patients with coronary heart disease: results from the CLARICOR trial

  Hilden, J., Lind, I., Kolmos, H. J., Als-Nielsen, B., Damgaard, M., Hansen, J. F., Hansen, S., Helø, O. H., Hildebrandt, P., Jensen, G. B., Kastrup, J., Kjøller, E., Nielsen, H., Petersen, L., Jespersen, C. M., Gluud, C. & CLARICOR Trial Group, 1 apr. 2010, I: Diagnostic Microbiology and Infectious Disease. 66, 4, s. 385-92 8 s.

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  • Chlamydophila pneumoniae 100%
  • Immunoglobulin A 71%
  • Coronary Disease 67%
  • Immunoglobulin G 57%
  • Clarithromycin 45%
  8 Citationer (Scopus)

• Development of a combined database for meta-epidemiological research

  Savović, J., Harris, R. J., Wood, L., Beynon, R., Altman, D., Als-Nielsen, B., Balk, E. M., Deeks, J., Gluud, L. L., Gluud, C., Ioannidis, J. P. A., Jűni, P., Moher, D., Pildal, J., Schulz, K. F. & Sterne, J. A. C., jul. 2010, I: Research Synthesis Methods. 1, 3-4, s. 212-25 14 s.

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  • Meta-Analysis 100%
  • Databases 80%
  • epidemiological studies 24%
  • Epidemiologic Studies 15%
  • Systematic Reviews 14%
  13 Citationer (Scopus)

• Statin treatment prevents increased cardiovascular and all-cause mortality associated with clarithromycin in patients with stable coronary heart disease

  Jensen, G. B., Hilden, J., Als-Nielsen, B., Damgaard, M., Hansen, J. F., Hansen, S., Helø, O. H., Hildebrandt, P., Kastrup, J., Kolmos, H. J., Kjøller, E., Lind, I., Nielsen, H., Petersen, L., Jespersen, C., Gluud, C. & CLARICOR Trial Group, 1 feb. 2010, I: Journal of Cardiovascular Pharmacology. 55, 2, s. 123-8 6 s.

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  • Clarithromycin 100%
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 81%
  • Coronary Disease 74%
  • Mortality 42%
  • Confidence Intervals 28%
  19 Citationer (Scopus)
• 2007

  Blinded trials taken to the test: an analysis of randomized clinical trials that report tests for the success of blinding

  Hróbjartsson, A., Forfang, E., Haahr, M. T., Als-Nielsen, B. & Brorson, S., 2007, I: International Journal of Epidemiology. 36, 3, s. 654-63 10 s.

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  • Randomized Controlled Trials 100%
  137 Citationer (Scopus)
• 2006

  Randomised placebo controlled multicentre trial to assess short term clarithromycin for patients with stable coronary heart disease: CLARICOR trial. CLARICOR trial

  Jespersen, C. M., Als-Nielsen, B., Damgaard, M., Hansen, J. F., Hansen, S., Helø, O. H., Hildebrandt, P., Hilden, J., Jensen, G. B., Kastrup, J., Kolmos, H. J. J., Kjøller, E., Lind, I., Nielsen, H., Petersen, L., Gluud, C. & CLARICOR Trial Group, 2006, I: B M J. 332, 7532, s. 22-7 6 s.

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  • Clarithromycin 100%
  • Coronary Disease 74%
  • Multicenter Studies 72%
  • Placebos 57%
  • Mortality 36%
  133 Citationer (Scopus)
• 2002

  Association between competing interests and authors' conclusions: epidemiological study of randomised clinical trials published in the BMJ

  Kjaergard, L. L. & Als-Nielsen, B., 3 aug. 2002, I: BMJ. 325, 7358, s. 249-252

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  • Epidemiologic Studies 100%
  • Randomized Controlled Trials 80%
  395 Citationer (Scopus)